Search Results
Overview
| Uniprot ID | B2RWM5 |
|---|---|
| Protein Name | Calponin |
| Gene Name | CNN2 |
| Organism | Homo sapiens |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 238 | DTKLGIDKCDNSSMS |
Function
Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity
Protein Sequence
10
SSTQFNKGPS
20
YGLSAEVKNR
30
LLSKYDPQKE
40
AELRTWIEGL
50
TGLSIGPDFQ
60
KGLKDGTILC
70
TLMNKLQPGS
80
VPKINRSMQN
90
WHQLENLSNF
100
IKAMVSYGMN
110
PVDLFEANDL
120
FESGNMTQVQ
130
VSLLALAGKA
140
KTKGLQSGVD
150
IGVKYSEKQE
160
RNFDDATMKA
170
GQCVIGLQMG
180
TNKCASQSGM
190
TAYGTRRHLY
200
DPKNHILPPM
210
DHSTISLQMG
220
TNKCASQVGM
230
TAPGTRRHIY
240
DTKLGIDKCD
250
NSSMSLQMGY
260
TQGANQSGQV
270
FGLGRQIYDP
280
KYCPQGTVAD
290
GAPSGTGDCP
300
DPGEVPEYPP
YYQEEAGY
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Molecular Function | GO:0003779 | actin binding |
| Molecular Function | GO:0005516 | calmodulin binding |
| Biological Process | GO:0031032 | actomyosin structure organization |
Reference
PMID: N/A