Search Results

Overview

Uniprot IDB2RYU7
Protein Name-
Gene NameCbx5
OrganismRattus norvegicus

Kla Sites from experimental identification

Position Flanking peptide
102 SNSADDIKSKKKREQ
32 VLDRRMVKGQVEYLL
91 KSEGNKRKSSFSNSA

Function

No function data available.

Protein Sequence

10 MGKKTKRTAD 20 SSSSEDEEEY 30 VVEKVLDRRM 40 VKGQVEYLLK 50 WKGFSEEHNT 60 WEPEKNLDCP 70 ELISEFMKKY 80 KKMKEGENNK 90 PREKSEGNKR 100 KSSFSNSADD 110 IKSKKKREQS 120 NDIARGFERG 130 LEPEKIIGAT 140 DSCGDLMFLM 150 KWKDTDEADL 160 VLAKEANVKC 170 PQIVIAFYEE 180 RLTWHAYPED 190 AENKEKESAK S

Gene Ontology

Classification GO ID Description
Cellular Component GO:0010369 chromocenter
Cellular Component GO:0000781 chromosome, telomeric region
Cellular Component GO:0000792 heterochromatin
Cellular Component GO:0000118 histone deacetylase complex
Cellular Component GO:0035097 histone methyltransferase complex
Cellular Component GO:0000776 kinetochore
Cellular Component GO:0005730 nucleolus
Cellular Component GO:0005654 nucleoplasm
Cellular Component GO:0005634 nucleus
Cellular Component GO:0005721 pericentric heterochromatin
Cellular Component GO:0016605 PML body
Cellular Component GO:0032991 protein-containing complex
Cellular Component GO:1990904 ribonucleoprotein complex
Cellular Component GO:0090734 site of DNA damage
Cellular Component GO:0017053 transcription repressor complex
Molecular Function GO:0003682 chromatin binding
Molecular Function GO:0140297 DNA-binding transcription factor binding
Molecular Function GO:0042826 histone deacetylase binding
Molecular Function GO:0160267 histone H1K26me1 reader activity
Molecular Function GO:0160268 histone H1K26me2 reader activity
Molecular Function GO:0062072 histone H3K9me2/3 reader activity
Molecular Function GO:0140566 histone reader activity
Molecular Function GO:0042802 identical protein binding
Molecular Function GO:0044877 protein-containing complex binding
Molecular Function GO:0030674 protein-macromolecule adaptor activity
Molecular Function GO:0043021 ribonucleoprotein complex binding
Biological Process GO:0030261 chromosome condensation
Biological Process GO:0006974 DNA damage response
Biological Process GO:0031507 heterochromatin formation
Biological Process GO:0070828 heterochromatin organization
Biological Process GO:0045892 negative regulation of DNA-templated transcription
Biological Process GO:0000122 negative regulation of transcription by RNA polymerase II
Biological Process GO:0097355 protein localization to heterochromatin

Reference

[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.

[2] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.