Search Results
Overview
| Uniprot ID | B2RYW7 |
|---|---|
| Protein Name | Signal recognition particle 14 kDa protein |
| Gene Name | Srp14 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 43 | RTKPIPRKSSVEGLE |
Function
Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding
Protein Sequence
10
MVLLESEQFL
20
TELTRLFQKC
30
RSSGSVFITL
40
KKYDGRTKPI
50
PRKSSVEGLE
60
PAENKCLLRA
70
TDGKRKISTV
80
VSSKEVNKFQ
90
MAYSNLLRAN
100
MDGLKKRDKK
110
NKSKKSKPAQ
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005786 | signal recognition particle, endoplasmic reticulum targeting |
| Molecular Function | GO:0008312 | 7S RNA binding |
| Molecular Function | GO:0030942 | endoplasmic reticulum signal peptide binding |
| Biological Process | GO:0006614 | SRP-dependent cotranslational protein targeting to membrane |
Reference
[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.