Search Results
Overview
| Uniprot ID | B2RZ37 |
|---|---|
| Protein Name | Receptor expression-enhancing protein 5 |
| Gene Name | Reep5 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 147 | VIRPIFLKHESQVDS |
| 157 | SQVDSVVKDVKDKAK |
| 164 | KDVKDKAKETADAIS |
| 172 | ETADAISKEVKKATV |
| 176 | AISKEVKKATVNLLG |
| 186 | VNLLGDEKKST**** |
Function
Plays an essential role in heart function and development by regulating the organization and function of the sarcoplasmic reticulum in cardiomyocytes
Protein Sequence
10
MSAAMRERFD
20
RFLHEKNCMT
30
DLLAKLEAKT
40
GVNRSFIALG
50
VIGLVALYLV
60
FGYGASLLCN
70
LIGFGYPAYI
80
SMKAIESPNK
90
DDDTQWLTYW
100
VVYGVFSIAE
110
FFSDLFLSWF
120
PFYYMLKCGF
130
LLWCMAPSPS
140
NGAELLYRRV
150
IRPIFLKHES
160
QVDSVVKDVK
170
DKAKETADAI
180
SKEVKKATVN
LLGDEKKST
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005783 | endoplasmic reticulum |
| Cellular Component | GO:0033017 | sarcoplasmic reticulum membrane |
| Biological Process | GO:0090158 | endoplasmic reticulum membrane organization |
| Cellular Component | GO:0071782 | endoplasmic reticulum tubular network |
| Cellular Component | GO:0014701 | junctional sarcoplasmic reticulum membrane |
Reference
[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.
[2] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.