Search Results
Overview
| Uniprot ID | B2RZ66 |
|---|---|
| Protein Name | Signal recognition particle 19 kDa protein |
| Gene Name | Srp19 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 121 | KLKTRTQKSGGADPS |
Function
Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). Binds directly to 7SL RNA. Mediates binding of SRP54 to the SRP complex
Protein Sequence
10
MACAAARSPA
20
DQDRFICIYP
30
AYLNNKKTIA
40
EGRRIPINKA
50
VENPTATEIQ
60
DVCSAVGLNA
70
FLEKNKMYSR
80
EWNRDVQYRG
90
RVRVQLKQED
100
GSLCLVQFPS
110
RKSVMLYVAE
120
MIPKLKTRTQ
130
KSGGADPSLQ
140
QGEGSKKGKG
KKKK
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005730 | nucleolus |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0048500 | signal recognition particle |
| Cellular Component | GO:0005786 | signal recognition particle, endoplasmic reticulum targeting |
| Molecular Function | GO:0008312 | 7S RNA binding |
| Molecular Function | GO:0043022 | ribosome binding |
| Molecular Function | GO:0003723 | RNA binding |
| Biological Process | GO:0006617 | SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition |
Reference
[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.