Search Results
Overview
| Uniprot ID | B3GNI6 |
|---|---|
| Protein Name | Septin-11 |
| Gene Name | Septin11 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 184 | NIIPIIAKADTIAKN |
| 190 | AKADTIAKNELHKFK |
| 366 | AEKELHEKFDLLKRT |
| 397 | EEVSNFQKKKAAAQL |
| 399 | VSNFQKKKAAAQLLQ |
Function
Filament-forming cytoskeletal GTPase. May play a role in cytokinesis (Potential). May play a role in the cytoarchitecture of neurons, including dendritic arborization and dendritic spines, and in GABAergic synaptic connectivity
Protein Sequence
10
MAVAVGRPSN
20
EELRNLSLSG
30
HVGFDSLPDQ
40
LVNKSTSQGF
50
CFNILCVGET
60
GIGKSTLMDT
70
LFNTKFESDP
80
ATHNEPGVRL
90
KARSYELQES
100
NVRLKLTIVD
110
TVGFGDQINK
120
DDSYKPIVEY
130
IDAQFEAYLQ
140
EELKIKRSLF
150
NYHDTRIHAC
160
LYFIAPTGHS
170
LKSLDLVTMK
180
KLDSKVNIIP
190
IIAKADTIAK
200
NELHKFKSKI
210
MSELVSNGVQ
220
IYQFPTDEET
230
VAEINATMSV
240
HLPFAVVGST
250
EEVKIGNKMA
260
KARQYPWGVV
270
QVENENHCDF
280
VKLREMLIRV
290
NMEDLREQTH
300
TRHYELYRRC
310
KLEEMGFKDT
320
DPDSKPFSLQ
330
ETYEAKRNEF
340
LGELQKKEEE
350
MRQMFVMRVK
360
EKEAELKEAE
370
KELHEKFDLL
380
KRTHQEEKKK
390
VEDKKKELEE
400
EVSNFQKKKA
410
AAQLLQSQAQ
420
QSGAQQTKKD
430
KDKKNPWLCT
E
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0030424 | axon |
| Cellular Component | GO:0032153 | cell division site |
| Cellular Component | GO:0043197 | dendritic spine |
| Cellular Component | GO:0098982 | GABA-ergic synapse |
| Cellular Component | GO:0098978 | glutamatergic synapse |
| Cellular Component | GO:0015630 | microtubule cytoskeleton |
| Cellular Component | GO:0098794 | postsynapse |
| Cellular Component | GO:0099629 | postsynaptic specialization of symmetric synapse |
| Cellular Component | GO:0031105 | septin complex |
| Cellular Component | GO:0005940 | septin ring |
| Cellular Component | GO:0001725 | stress fiber |
| Molecular Function | GO:0005525 | GTP binding |
| Molecular Function | GO:0003924 | GTPase activity |
| Molecular Function | GO:0060090 | molecular adaptor activity |
| Biological Process | GO:0061640 | cytoskeleton-dependent cytokinesis |
| Biological Process | GO:0008104 | intracellular protein localization |
| Biological Process | GO:0050807 | regulation of synapse organization |
Reference
[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.