Search Results
Overview
| Uniprot ID | B4F450 |
|---|---|
| Protein Name | Ubiquitin-like protein 5 |
| Gene Name | UBL5 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 29 | DTIGDLKKLIAAQTG |
| 41 | QTGTRWNKIVLKKWY |
| 46 | WNKIVLKKWYTIFKD |
Function
Ubiquitin-like protein that plays a role in cell proliferation and sister chromatid cohesion by associating with spliceosomal proteins. Participates thereby in pre-mRNA splicing by maintaining spliceosome integrity. Promotes the functional integrity of the Fanconi anemia DNA repair pathway by interacting with FANCI component and subsequently mediating the formation of FANCI homodimers. Also plays a protective role against ER stress-induced apoptosis
Protein Sequence
10
MIEVVCNDRL
20
GKKVRVKCNT
30
DDTIGDLKKL
40
IAAQTGTRWN
50
KIVLKKWYTI
60
FKDHVSLGDY
70
EIHDGMNLEL
YYQ
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0031386 | protein tag activity |
| Biological Process | GO:0000398 | mRNA splicing, via spliceosome |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.