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Overview

Uniprot IDB5DEL8
Protein NameNADH dehydrogenase [ubiquinone] iron-sulfur protein 5
Gene NameNdufs5
OrganismRattus norvegicus

Kla Sites from experimental identification

Position Flanking peptide
8 MPFLDVQKRLGISLD

Function

Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone

Protein Sequence

10 MPFLDVQKRL 20 GISLDRHFIF 30 LSAEQPYKNA 40 ARCHAFEKEW 50 IECAHGIGAT 60 RAKKECKIEY 70 EDFEECFLRF 80 KTIRRMHEIK 90 KQREKLMKEG 100 KYTPPPHHLG KEEPRP

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005743 mitochondrial inner membrane
Cellular Component GO:0005758 mitochondrial intermembrane space
Cellular Component GO:0005739 mitochondrion
Cellular Component GO:0045271 respiratory chain complex I
Biological Process GO:0032981 mitochondrial respiratory chain complex I assembly
Biological Process GO:0022904 respiratory electron transport chain

Reference

[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.