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Overview

Uniprot IDB5DEM5
Protein NameLarge ribosomal subunit protein eL14
Gene NameRpl14
OrganismRattus norvegicus

Kla Sites from experimental identification

Position Flanking peptide
103 DARERKAKMTDFDRF
137 LQRAALLKASPKKAA
147 PKKAAVAKAAIAAAA
157 IAAAAAAKAKVPAKK
171 KATGPGQKAAGQKAA
191 AQKAAGQKAAPPAKG
208 GQKTPAQKAPAPKAA

Function

Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell

Protein Sequence

10 MVFRRFVEVG 20 RVAYISFGPH 30 AGKLVAIVDV 40 IDQNRALVDG 50 PCTRVRRQAM 60 PFKCMQLTDF 70 ILKFPHSARQ 80 KYVRKAWEKA 90 DINTKWAATR 100 WAKKIDARER 110 KAKMTDFDRF 120 KVMKAKKMRN 130 RIIKTEVKKL 140 QRAALLKASP 150 KKAAVAKAAI 160 AAAAAAKAKV 170 PAKKATGPGQ 180 KAAGQKAAGQ 190 KASAQKAAGQ 200 KAAPPAKGQK 210 GQKTPAQKAP APKAAGKKA

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005737 cytoplasm
Cellular Component GO:0015934 large ribosomal subunit
Molecular Function GO:0003723 RNA binding
Molecular Function GO:0003735 structural constituent of ribosome
Biological Process GO:0006412 translation

Reference

[1] Yao Y, Bade R, Li G, Zhang A, Zhao H et al.. Global-Scale Profiling of Differential Expressed Lysine-Lactylated Proteins in the Cerebral Endothelium of Cerebral Ischemia-Reperfusion Injury Rats.. Cell Mol Neurobiol 43(5):1989-2004. 2023 Jul. PMID: 36030297.

[2] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.