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Overview

Uniprot ID	B5DF63
Protein Name	Sarcolemmal membrane-associated protein
Gene Name	Slmap
Organism	Rattus norvegicus

Kla Sites from experimental identification

Position	Flanking peptide
63	ALVWFDHKTSKFYLQ

Function

Associates with the striatin-interacting phosphatase and kinase (STRIPAK) core complex, forming the extended (SIKE1:SLMAP)STRIPAK complex. The (SIKE1:SLMAP)STRIPAK complex dephosphorylates STK3 leading to the inhibition of Hippo signaling and the control of cell growth. May play a role during myoblast fusion

Protein Sequence

10 MPSALAIFTC 20 RPNSHPFQER 30 HVYLDEPIKI 40 GRSVARCRPA 50 QNNATFDCKV 60 LSRNHALVWF 70 DHKTSKFYLQ 80 DTKSSNGTFI 90 NSQRLSRGSE 100 ESPPCEILSG 110 DIIQFGVDVT 120 ENTRKVTHGC 130 IVSTIKLFLP 140 DGMEARLRSD 150 VIHAPLPSPV 160 DKVAANTPSM 170 YSQELFQLSQ 180 YLQEALHREQ 190 MLEQKLATLQ 200 RLLAITQEAS 210 DTSWQALIDE 220 DRLLSRLEVM 230 GNQLQACSKN 240 QTEDSLRKEL 250 VALQEDKHSY 260 ETTAKESLRR 270 VLQEKIEVVR 280 KLSEVERSLS 290 NTEDECTHLR 300 EMNERTQEEL 310 RELANKYNGA 320 VNEIKDLSDK 330 LKAAEGKQEE 340 IQQKGQAEKK 350 ELQAKIDDME 360 EKEQELQAKI 370 EALQADNDFT 380 NERLTALQEK 390 LMVQGHLTKV 400 VEESKLSKEN 410 QAKAKESDLS 420 DTLSPSKEKS 430 SDDTTDAQMD 440 EQDLNEPLAK 450 VSLLKALLEE 460 ERKAYRNQVE 470 ESAKQIQVLQ 480 VQLQRLHMDM 490 ENLQEEKDTE 500 ISSTRDKLLS 510 AQDEILLLHQ 520 AAAKAVSERD 530 TDFMSLQEEL 540 KKVRAELEGW 550 RKAASEYEEE 560 IRSLQSTFQL 570 RCQQCEVQQR 580 EEATRLQGEL 590 EKLKKEWDVL 600 ENECRSLKKE 610 NVLLSSELQR 620 QEKELHNSQK 630 QSLELTSDLS 640 ILQMTRKELE 650 NQMGSLKEQH 660 LRDEADLKTL 670 LSKAENQAKD 680 VQKEYEKTQT 690 VLSELKLKFE 700 MTEQEKQSIT 710 DELKQCKDNL 720 KLLREKGNNK 730 PWPWMPMVAA 740 LVAVTAMVLY VPGLARASP

Gene Ontology

Classification	GO ID	Description
Cellular Component	GO:0005813	centrosome
Cellular Component	GO:0005789	endoplasmic reticulum membrane
Cellular Component	GO:0031966	mitochondrial membrane
Cellular Component	GO:0042383	sarcolemma

Reference

[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.