Search Results
Overview
| Uniprot ID | B8XH67 |
|---|---|
| Protein Name | Na(+)/H(+) exchange regulatory cofactor NHE-RF |
| Gene Name | SLC9A3R1 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 247 | RETDEFFKKCKVIPS |
Function
Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression
Protein Sequence
10
MSADSAAGAP
20
LPRLCCLEKG
30
PNGYGFHLHG
40
EKGKVGQFIR
50
LVEPGSPAEK
60
SGLLAGDRLV
70
EVNGENVEKE
80
THQQVVSRIR
90
AALNAVRLLV
100
VDPETDERLQ
110
KLGVQVREEM
120
LRAQEGPGQA
130
EPPAATEAQG
140
ADSENEPPAA
150
TPEPHEAEKS
160
RQEPRELRPR
170
LCAMKKGPNG
180
YGFNLHSDKS
190
KPGQFIRAVD
200
PDSPAEASGL
210
RAQDRIVEVN
220
GVCVEGKQHG
230
DVVSAIKAGG
240
DEAKLLVVDR
250
ETDEFFKKCK
260
VIPSQEHLSG
270
PLPEPFTNGE
280
IQKENSGEAP
290
AEAASESPMP
300
TLARSTSSDT
310
SEELNSQDSP
320
KKEDTAASST
330
SSSSDPVLDF
340
NISLAVAKER
350
AHQKRSSKRA
360
PQMDWSKKNE
LFSNL
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0016324 | apical plasma membrane |
| Cellular Component | GO:0031526 | brush border membrane |
| Cellular Component | GO:0012505 | endomembrane system |
| Cellular Component | GO:0030175 | filopodium |
| Cellular Component | GO:0005902 | microvillus |
| Cellular Component | GO:0048471 | perinuclear region of cytoplasm |
| Cellular Component | GO:0001726 | ruffle |
| Cellular Component | GO:0097225 | sperm midpiece |
| Cellular Component | GO:0032426 | stereocilium tip |
| Molecular Function | GO:0031698 | beta-2 adrenergic receptor binding |
| Molecular Function | GO:0008013 | beta-catenin binding |
| Molecular Function | GO:0099103 | channel activator activity |
| Molecular Function | GO:0017081 | chloride channel regulator activity |
| Molecular Function | GO:0050780 | dopamine receptor binding |
| Molecular Function | GO:0070851 | growth factor receptor binding |
| Molecular Function | GO:0042802 | identical protein binding |
| Molecular Function | GO:0030165 | PDZ domain binding |
| Molecular Function | GO:0019902 | phosphatase binding |
| Molecular Function | GO:0043495 | protein-membrane adaptor activity |
| Molecular Function | GO:0005102 | signaling receptor binding |
| Molecular Function | GO:0031799 | type 2 metabotropic glutamate receptor binding |
| Molecular Function | GO:0031800 | type 3 metabotropic glutamate receptor binding |
| Biological Process | GO:0032782 | bile acid secretion |
| Biological Process | GO:0044782 | cilium organization |
| Biological Process | GO:0045198 | establishment of epithelial cell apical/basal polarity |
| Biological Process | GO:0051683 | establishment of Golgi localization |
| Biological Process | GO:0022612 | gland morphogenesis |
| Biological Process | GO:0034635 | glutathione transport |
| Biological Process | GO:0045199 | maintenance of epithelial cell apical/basal polarity |
| Biological Process | GO:0030033 | microvillus assembly |
| Biological Process | GO:0090090 | negative regulation of canonical Wnt signaling pathway |
| Biological Process | GO:2000146 | negative regulation of cell motility |
| Biological Process | GO:0008285 | negative regulation of cell population proliferation |
| Biological Process | GO:0070373 | negative regulation of ERK1 and ERK2 cascade |
| Biological Process | GO:0045930 | negative regulation of mitotic cell cycle |
| Biological Process | GO:0051898 | negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction |
| Biological Process | GO:0010642 | negative regulation of platelet-derived growth factor receptor signaling pathway |
| Biological Process | GO:0007097 | nuclear migration |
| Biological Process | GO:0007009 | plasma membrane organization |
| Biological Process | GO:2001244 | positive regulation of intrinsic apoptotic signaling pathway |
| Biological Process | GO:0072659 | protein localization to plasma membrane |
| Biological Process | GO:0008360 | regulation of cell shape |
| Biological Process | GO:0008361 | regulation of cell size |
| Biological Process | GO:0097291 | renal phosphate ion absorption |
| Biological Process | GO:0016055 | Wnt signaling pathway |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.