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Overview

Uniprot IDC6T977
Protein NameADP/ATP translocase
Gene Name-
OrganismGlycine max

Kla Sites from experimental identification

Position Flanking peptide
107 QNQDEMIKSGRLSEP
231 DVYRKTIKSDGVAGL
313 MTSGEAVKYKSSLHA

Function

ADP:ATP antiporter that mediates import of ADP into the mitochondrial matrix for ATP synthesis, and export of ATP out to fuel the cell. Cycles between the cytoplasmic-open state (c-state) and the matrix-open state (m-state): operates by the alternating access mechanism with a single substrate-binding site intermittently exposed to either the cytosolic (c-state) or matrix (m-state) side of the inner mitochondrial membrane

Protein Sequence

10 MADGPQHPSV 20 VQKLAGQSYL 30 VSRLSPNFNS 40 GNYSSTGSYF 50 NGGLHSSGLA 60 VVSPGSPVTV 70 HAPAEKGVSG 80 FLVDFLMGGV 90 SAAVSKTAAA 100 PIERVKLLIQ 110 NQDEMIKSGR 120 LSEPYKGIGD 130 CFARTMKDEG 140 VIALWRGNTA 150 NVIRYFPTQA 160 LNFAFKDYFK 170 RLFNFKKDKD 180 GYWKWFAGNL 190 ASGGAAGASS 200 LLFVYSLDYA 210 RTRLANDAKA 220 AKKGGERQFN 230 GLVDVYRKTI 240 KSDGVAGLYR 250 GFNISCVGII 260 VYRGLYFGMY 270 DSLKPVVLVG 280 GLQDSFFASF 290 LLGWGITIGA 300 GLASYPIDTV 310 RRRMMMTSGE 320 AVKYKSSLHA 330 FQTIVANEGA 340 KSLFKGAGAN 350 ILRAVAGAGV 360 LAGYDKLQLV 370 LFGKKYGSGG GG

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005743 mitochondrial inner membrane
Cellular Component GO:0005757 mitochondrial permeability transition pore complex
Molecular Function GO:0005471 ATP:ADP antiporter activity
Biological Process GO:0140021 mitochondrial ADP transmembrane transport
Biological Process GO:1990544 mitochondrial ATP transmembrane transport
Biological Process GO:0046902 regulation of mitochondrial membrane permeability

Reference

[1] Xu C, Li J, Dong C, Zhang Y, Li H et al.. Lactylome Profiling Reveals the Potential Role of Lysine Lactylation in Regulating Soybean Seed Quality.. J Agric Food Chem 73(23):14666-14676. 2025 Jun 11. PMID: 40440508.