Search Results

Overview

Uniprot ID	D0G0C9
Protein Name	T-complex protein 1 subunit eta
Gene Name	CCT7
Organism	Sus scrofa

Kla Sites from experimental identification

Position	Flanking peptide
135	ATQLAVNKIKEIAVT
137	QLAVNKIKEIAVTVK
144	KEIAVTVKKEDKVEQ
157	EQRKLLEKCAMTALS
172	SKLISQQKAFFAKMV
218	VAGVAFKKTFSYAGF
250	ELELKAEKDNAEIRV
287	RIYHSGAKVVLSKLP
320	RVPEEDLKRTMMACG
366	NFFTGCPKAKTCTII
368	FTGCPKAKTCTIILR
430	YSRTIPGKQQLLIGA
47	LGPRGMDKLIVDGRG
55	LIVDGRGKATISNDG
77	DVVHPAAKTLVDIAK

Function

Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of actin, tubulin and other proteins upon ATP hydrolysis. The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance

Protein Sequence

10 MMPTPVILLK 20 EGTDSSQGIP 30 QLVSNISACQ 40 VIAEAVRTTL 50 GPRGMDKLIV 60 DGRGKATISN 70 DGATILKLLD 80 VVHPAAKTLV 90 DIAKSQDAEV 100 GDGTTSVTLL 110 AAEFLKQVKP 120 YVEEGLHPQI 130 IIRAFRTATQ 140 LAVNKIKEIA 150 VTVKKEDKVE 160 QRKLLEKCAM 170 TALSSKLISQ 180 QKAFFAKMVV 190 DAVMMLDDLL 200 QLKMIGIKKV 210 QGGALEESQL 220 VAGVAFKKTF 230 SYAGFEMQPK 240 KYHNPMIALL 250 NVELELKAEK 260 DNAEIRVHTV 270 EDYQAIVDAE 280 WNILYDKLER 290 IYHSGAKVVL 300 SKLPIGDVAT 310 QYFADRDMFC 320 AGRVPEEDLK 330 RTMMACGGSI 340 QTSVNALSSD 350 VLGRCQVFEE 360 TQIGGERYNF 370 FTGCPKAKTC 380 TIILRGGAEQ 390 FMEETERSLH 400 DAIMIVRRAI 410 KNDSVVAGGG 420 AIEMELSKYL 430 RDYSRTIPGK 440 QQLLIGAYAK 450 ALEIIPRQLC 460 DNAGFDATNI 470 LNKLRARHAQ 480 GGTWYGVDIN 490 NEDIADNFEA 500 FVWEPAMVRI 510 NALTAASEAA 520 CLIVSVDETI 530 KNPRSTVDAP 540 PAAGRGRGRG RPH

Gene Ontology

Classification	GO ID	Description
Cellular Component	GO:0005832	chaperonin-containing T-complex
Molecular Function	GO:0005524	ATP binding
Molecular Function	GO:0016887	ATP hydrolysis activity
Molecular Function	GO:0140662	ATP-dependent protein folding chaperone
Molecular Function	GO:0051082	unfolded protein binding

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.