Search Results
Overview
| Uniprot ID | D0G7F6 |
|---|---|
| Protein Name | Triosephosphate isomerase |
| Gene Name | TPI1 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 142 | REAGITEKVVFEQTK |
| 149 | KVVFEQTKVIADNVK |
| 156 | KVIADNVKDWNKVVL |
| 188 | QAQEVHEKLRGWLKT |
| 19 | NWKMNGRKNNLGELI |
| 194 | EKLRGWLKTHVSEAV |
| 59 | ARQKLDPKIAVAAQN |
| 6 | **MAPARKFFVGGNW |
Function
It is also responsible for the non-negligible production of methylglyoxal a reactive cytotoxic side-product that modifies and can alter proteins, DNA and lipids
Protein Sequence
10
MAPARKFFVG
20
GNWKMNGRKN
30
NLGELINTLN
40
AAKLPADTEV
50
VCAPPTAYID
60
FARQKLDPKI
70
AVAAQNCYKV
80
ANGAFTGEIS
90
PGMIKDLGAT
100
WVVLGHSERR
110
HVFGESDELI
120
GQKVAHALAE
130
GLGVIACIGE
140
KLDEREAGIT
150
EKVVFEQTKV
160
IADNVKDWNK
170
VVLAYEPVWA
180
IGTGKTATPQ
190
QAQEVHEKLR
200
GWLKTHVSEA
210
VAQSTRIIYG
220
GSVTGATCKE
230
LASQPDVDGF
240
LVGGASLKPE
FVDIINAK
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Molecular Function | GO:0008929 | methylglyoxal synthase activity |
| Molecular Function | GO:0004807 | triose-phosphate isomerase activity |
| Biological Process | GO:0006094 | gluconeogenesis |
| Biological Process | GO:0006096 | glycolytic process |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.