Search Results
Overview
| Uniprot ID | D2IE28 |
|---|---|
| Protein Name | G2/mitotic-specific cyclin-B1 |
| Gene Name | CCNB1 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 73 | AKTLAAGKVVAKKLP |
Function
Essential for the control of the cell cycle at the G2/M (mitosis) transition
Protein Sequence
10
MALRITRNTK
20
INAENKAKIS
30
MAGAKRVPVA
40
SAATSKPGLR
50
PRTALGDIGN
60
KVSEQPQAKL
70
PLKKEAKTLA
80
AGKVVAKKLP
90
KPLEKAPVPV
100
LEPQPEREPE
110
PELEPEPEPE
120
PVKGEKLSPE
130
PILVDTPSPS
140
PMETSGCAPA
150
EEYLCQAFSD
160
VILAVNDVDA
170
EDGGDPNLCS
180
EYVKDIYDYL
190
RQLEEEQAVR
200
PKYLLGREVT
210
GNMRAILIDW
220
LVQVQMKFRL
230
LQETMYMTVS
240
IIDRFMQDNC
250
VPKKMLQLVG
260
VTAMFIASKY
270
EEMYPPEIGD
280
FAFVTDNTYT
290
KYQIRQMEMK
300
ILRALNFCLG
310
RPLPLHFLRR
320
ASKIGEVDVE
330
LHTLAKYLME
340
LTMLDYDMVH
350
FPPSQIAAGA
360
FCLSLKILDN
370
GEWTPTLQHY
380
LSYTEESLLV
390
VMQHLAKNIV
400
VVNRGLTKHM
410
TIKNKYATSK
420
HAKISTLAQL
430
NSALVQDLAK
AVAKV
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005813 | centrosome |
| Cellular Component | GO:0097125 | cyclin B1-CDK1 complex |
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0016020 | membrane |
| Cellular Component | GO:0005815 | microtubule organizing center |
| Cellular Component | GO:0005759 | mitochondrial matrix |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0000940 | outer kinetochore |
| Cellular Component | GO:0000922 | spindle pole |
| Molecular Function | GO:0061575 | cyclin-dependent protein serine/threonine kinase activator activity |
| Molecular Function | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity |
| Molecular Function | GO:0035173 | histone kinase activity |
| Molecular Function | GO:0005113 | patched binding |
| Molecular Function | GO:0019901 | protein kinase binding |
| Molecular Function | GO:0044389 | ubiquitin-like protein ligase binding |
| Biological Process | GO:0051301 | cell division |
| Biological Process | GO:0000082 | G1/S transition of mitotic cell cycle |
| Biological Process | GO:0007080 | mitotic metaphase chromosome alignment |
| Biological Process | GO:0007052 | mitotic spindle organization |
| Biological Process | GO:1904145 | negative regulation of meiotic cell cycle process involved in oocyte maturation |
| Biological Process | GO:0051987 | positive regulation of attachment of spindle microtubules to kinetochore |
| Biological Process | GO:0010971 | positive regulation of G2/M transition of mitotic cell cycle |
| Biological Process | GO:1905448 | positive regulation of mitochondrial ATP synthesis coupled electron transport |
| Biological Process | GO:0090266 | regulation of mitotic cell cycle spindle assembly checkpoint |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.