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Overview

Uniprot IDD2WL18
Protein NameF-box only protein 7
Gene NameFBXO7
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
397 RGRDTDWKELYKKRH

Function

No function data available.

Protein Sequence

10 MKLRVRLQKR 20 TWPLEMPEAE 30 PTLGQLRAHL 40 SQALLPTCGY 50 SSDARFAITL 60 NNKDALTGDE 70 ETLASYGIVS 80 GDLICLILED 90 AIPAPNLPSS 100 TDSEHSSLQN 110 NDQPSLAASF 120 SPSGIQDEQL 130 SDSFQGQAAQ 140 SDVWNDDSMS 150 GPSQNSEAEP 160 DQDVVDMEEG 170 TGFYPSEPML 180 CSESVEGQVP 190 HSLETLYQSA 200 DCSSPSDALI 210 VSIHLLMLES 220 GYMPQGTEAR 230 AVSMPENWRS 240 GGVYKLQYTH 250 PLCEGGSAAL 260 TCVPLGNLIV 270 INATLKLNSE 280 IRSVKRLQLL 290 PESFICKEES 300 ENVLGENVAK 310 IYKDLQKLSR 320 LFKDQLVYPL 330 LAFTRQALNL 340 PDVFGLVVLP 350 LELKLRIFRL 360 LDVRSVLSLS 370 AVCRDLYIAS 380 NDQLLWRCLY 390 LRDFRDGTVR 400 GRDTDWKELY 410 KKRHKQRKEA 420 QRGRHVMFLP 430 SSPHPIPFYP 440 NPLHPRPFPP 450 SSLLPPGIIG 460 GEYDERITLP 470 YVGDPINSLI 480 PGPGETPSQF 490 PPLRPRFDPI 500 GPLPGPNPIL 510 PGRGGPNDRF 520 PLRPSRGRPT DSRLPFM

Gene Ontology

Classification GO ID Description
Cellular Component GO:0097414 classical Lewy body
Cellular Component GO:0005829 cytosol
Cellular Component GO:0097409 glial cytoplasmic inclusion
Cellular Component GO:1990037 Lewy body core
Cellular Component GO:1990038 Lewy body corona
Cellular Component GO:0097462 Lewy neurite
Cellular Component GO:0005739 mitochondrion
Cellular Component GO:0005654 nucleoplasm
Cellular Component GO:0019005 SCF ubiquitin ligase complex
Molecular Function GO:0046982 protein heterodimerization activity
Molecular Function GO:0019901 protein kinase binding
Molecular Function GO:0043130 ubiquitin binding
Molecular Function GO:0031625 ubiquitin protein ligase binding
Molecular Function GO:1990756 ubiquitin-like ligase-substrate adaptor activity
Biological Process GO:0000422 autophagy of mitochondrion
Biological Process GO:0043124 negative regulation of canonical NF-kappaB signal transduction
Biological Process GO:1903599 positive regulation of autophagy of mitochondrion
Biological Process GO:1901526 positive regulation of mitophagy
Biological Process GO:0070936 protein K48-linked ubiquitination
Biological Process GO:0006626 protein targeting to mitochondrion
Biological Process GO:0040012 regulation of locomotion
Biological Process GO:0010975 regulation of neuron projection development
Biological Process GO:0031647 regulation of protein stability
Biological Process GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.