Search Results
Overview
| Uniprot ID | D3ZCP9 |
|---|---|
| Protein Name | Transcription initiation factor IIE subunit beta |
| Gene Name | Gtf2e2 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 74 | NNGSFNLKALSGSSG |
Function
Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase
Protein Sequence
10
MMNSNVEVIM
20
DPSLLRDREL
30
FKKRALSTPV
40
VEKRAVPSES
50
PSSSSKKKKA
60
KVEHGGSSGS
70
KQNSDHNNGS
80
FNLKALSGSS
90
GYKFGVLAKI
100
VNYMKTRHQR
110
GDTHPLTLEE
120
ILDETQHLDI
130
GLKQKQWLMT
140
EALVNNPKIE
150
VVDGKYAFKP
160
KYNLKDKKAL
170
LRLLDNHDQR
180
GLGGILLEDI
190
EEGLPNSQKA
200
VKALGDQILF
210
VSRPDKKKIL
220
FFNDKSCQFS
230
VDEEFQKLWR
240
SVTVDSMDEE
250
KIEEYLKRQG
260
ISSMQESGPK
270
KVASIQRRKK
280
PASQKKRRFK
290
THNEHLAGVL
300
KDYSDITPGK
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0005669 | transcription factor TFIID complex |
| Cellular Component | GO:0005673 | transcription factor TFIIE complex |
| Molecular Function | GO:0003677 | DNA binding |
| Molecular Function | GO:0016251 | RNA polymerase II general transcription initiation factor activity |
| Biological Process | GO:0051123 | RNA polymerase II preinitiation complex assembly |
| Biological Process | GO:0006366 | transcription by RNA polymerase II |
| Biological Process | GO:0006367 | transcription initiation at RNA polymerase II promoter |
Reference
[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.