Search Results
Overview
| Uniprot ID | D3ZLF6 |
|---|---|
| Protein Name | - |
| Gene Name | Snrpa1 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 149 | KRGAQLAKDIARRSK |
| 156 | KDIARRSKTFNPGAG |
| 168 | GAGLPTDKKKGGPSA |
| 170 | GLPTDKKKGGPSAGD |
| 198 | LAEVERLKGLLQSGQ |
Function
Involved in pre-mRNA splicing as component of the spliceosome. Associated with sn-RNP U2, where it contributes to the binding of stem loop IV of U2 snRNA
Protein Sequence
10
MAREGYKIPV
20
IENLGATLDQ
30
FDAIDFSDNE
40
IRKLDGFPLL
50
RRLKTLLVNN
60
NRICRIGEGL
70
DQALPCLTEL
80
ILTNNSLVEL
90
GDLDPLASLK
100
SLTYLSILRN
110
PVTNKKHYRL
120
YVIYKVPQVR
130
VLDFQKVKLK
140
ERQEAEKMFK
150
GKRGAQLAKD
160
IARRSKTFNP
170
GAGLPTDKKK
180
GGPSAGDVEA
190
IKNAIANAST
200
LAEVERLKGL
210
LQSGQIPGRE
220
RRSGPSDEGE
230
EEMEDGTVTN
GS
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0030532 | small nuclear ribonucleoprotein complex |
| Cellular Component | GO:0005681 | spliceosomal complex |
| Molecular Function | GO:0030620 | U2 snRNA binding |
| Biological Process | GO:0000398 | mRNA splicing, via spliceosome |
Reference
[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.
[2] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.