Search Results
Overview
| Uniprot ID | D3ZQV8 |
|---|---|
| Protein Name | PHD finger protein 6 |
| Gene Name | Phf6 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 173 | RPRKTNLKGLAEDTR |
| 26 | FCKSNRDKECGQLLI |
Function
Transcriptional regulator that associates with ribosomal RNA promoters and suppresses ribosomal RNA (rRNA) transcription
Protein Sequence
10
MSSSIEQKKG
20
STRQRKCGFC
30
KSNRDKECGQ
40
LLISENQKVA
50
AHHKCMLFSS
60
ALVSSHSDNE
70
SLGGFSIEDV
80
QKEIKRGTKL
90
MCSLCHCPGA
100
TIGCDVKTCH
110
RTYHYHCALH
120
DKAQIREKPS
130
QGIYMVYCRK
140
HKKTAHNSEA
150
DLEESFNEHE
160
LEPSSPKTKK
170
KSRKGRPRKT
180
NLKGLAEDTR
190
STSSHGTDET
200
ESSSYRDRSP
210
HRSSPNDTRP
220
KCGFCHVGEE
230
ENEARGKLHI
240
FNAKKAAAHY
250
KCMLFSSGTV
260
QLTTTSRAEF
270
GDFDIKTVLQ
280
EIKRGKRMKC
290
TLCSQPGATI
300
GCEIKACVKT
310
YHYHCGVQDK
320
AKYIENMSRG
330
IYKLYCKNHS
340
GNDERDEEDE
350
ERESKSRGRV
360
AIDQQLTQQQ
LNGN
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0000776 | kinetochore |
| Cellular Component | GO:0005730 | nucleolus |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0003677 | DNA binding |
| Molecular Function | GO:0019899 | enzyme binding |
| Molecular Function | GO:0042393 | histone binding |
| Molecular Function | GO:0042826 | histone deacetylase binding |
| Molecular Function | GO:0051219 | phosphoprotein binding |
| Molecular Function | GO:0043021 | ribonucleoprotein complex binding |
| Molecular Function | GO:0097110 | scaffold protein binding |
| Molecular Function | GO:0015631 | tubulin binding |
| Molecular Function | GO:0008270 | zinc ion binding |
| Biological Process | GO:0001835 | blastocyst hatching |
| Biological Process | GO:0006351 | DNA-templated transcription |
| Biological Process | GO:0000122 | negative regulation of transcription by RNA polymerase II |
| Biological Process | GO:0006357 | regulation of transcription by RNA polymerase II |
Reference
[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.