Search Results
Overview
| Uniprot ID | D3ZRK7 |
|---|---|
| Protein Name | Cell division control protein |
| Gene Name | Cdc6 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 413 | VRSQTVLKPLSECKS |
Function
Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated
Protein Sequence
10
MPQTRSQTQA
20
TIDFPKKKQS
30
KTLSKTNSRD
40
SEVKLRNVQP
50
VPTTPCADIK
60
ILPLSPRKRL
70
GDDNLCNTPH
80
LSPCSPPKLG
90
RKENGPPRSH
100
TRKGCRLIFD
110
DELAVKASAP
120
KEQDRVPQHQ
130
ILSSAQRGQE
140
SETNPEQKCP
150
PEKESACMRL
160
FKQEGTCYQQ
170
AKLVLNTAVP
180
DRLPAREQEM
190
GVIRDFLKEH
200
ICGKKAGSLY
210
LSGAPGTGKT
220
ACLSRILQDF
230
KKEVKGFKTI
240
VLNCMSLRNA
250
QAVFPAIAQE
260
IGREELCRPT
270
GKDLMRKLEK
280
HLTAERGPMI
290
VLVLDEMDQL
300
DSKGQDVLYT
310
LFEWPWLSNS
320
RLVLIGIANT
330
LDLTDRILPR
340
LEAREGCKPK
350
LLNFPPYTRN
360
QIAAILQDRL
370
SQVSKDQVLD
380
SAAIQFCARK
390
VSAVSGDIRK
400
ALDVCRRAIE
410
IVESDVRSQT
420
VLKPLSECKS
430
PCESLVPKRV
440
GLAHISQVIS
450
GVDGNRVTLS
460
QENTQDSLPL
470
QQKILVCSLL
480
LLTKRLKIKE
490
VTLGKLYEAY
500
SSVCRKQQVA
510
AVDQSECLSL
520
SGLLESRGIV
530
GLKKNKESRL
540
TKVSLKIEEK
550
EIEHVLKGKA
560
FIGNILAAGL
P
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Biological Process | GO:0051301 | cell division |
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0005819 | spindle |
| Cellular Component | GO:0051233 | spindle midzone |
| Cellular Component | GO:0000922 | spindle pole |
| Molecular Function | GO:0005524 | ATP binding |
| Molecular Function | GO:0016887 | ATP hydrolysis activity |
| Molecular Function | GO:0003682 | chromatin binding |
| Molecular Function | GO:0003688 | DNA replication origin binding |
| Molecular Function | GO:0120283 | protein serine/threonine kinase binding |
| Biological Process | GO:1904385 | cellular response to angiotensin |
| Biological Process | GO:1904117 | cellular response to vasopressin |
| Biological Process | GO:0006270 | DNA replication initiation |
| Biological Process | GO:0033314 | mitotic DNA replication checkpoint signaling |
| Biological Process | GO:0051984 | positive regulation of chromosome segregation |
| Biological Process | GO:0045737 | positive regulation of cyclin-dependent protein serine/threonine kinase activity |
| Biological Process | GO:0032467 | positive regulation of cytokinesis |
| Biological Process | GO:0048146 | positive regulation of fibroblast proliferation |
| Biological Process | GO:0030071 | regulation of mitotic metaphase/anaphase transition |
Reference
[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.