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Overview

Uniprot IDD3ZUB0
Protein NameReticulocalbin-1
Gene NameRcn1
OrganismRattus norvegicus

Kla Sites from experimental identification

Position Flanking peptide
116 YIYDNVAKVWKDYDR
170 PRDERRFKASDLDGD
290 VYESDKNKDEMLTKE
75 QLSPDESKERLGKIV

Function

May regulate calcium-dependent activities in the endoplasmic reticulum lumen or post-ER compartment

Protein Sequence

10 MARGGRLGLA 20 LGLLLALVLA 30 LRAKPTVRKE 40 RVVRPDSELG 50 ERPPEDNQSF 60 QYDHEAFLGK 70 EDSKTFDQLS 80 PDESKERLGK 90 IVDRIDSDGD 100 GLVTTEELKV 110 WIKRVQKRYI 120 YDNVAKVWKD 130 YDRDKDEKIS 140 WEEYKQATYG 150 YYLGNPAEFQ 160 DSSDHHTFKK 170 MLPRDERRFK 180 ASDLDGDLTA 190 TREEFTAFLH 200 PEEFEHMKEI 210 VVLETLEDID 220 KNGDGFVDQD 230 EYIADMFSHE 240 DNGPEPDWVL 250 SEREQFNDFR 260 DLNKDGKLDK 270 DEIRHWILPQ 280 DYDHAQAEAR 290 HLVYESDKNK 300 DEMLTKEEIL 310 DNWNMFVGSQ 320 ATNYGEDLTK NHDEL

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005783 endoplasmic reticulum
Cellular Component GO:0005788 endoplasmic reticulum lumen
Molecular Function GO:0005509 calcium ion binding
Biological Process GO:0043010 camera-type eye development
Biological Process GO:0001701 in utero embryonic development

Reference

[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.