Search Results
Overview
| Uniprot ID | D3ZVK3 |
|---|---|
| Protein Name | tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 |
| Gene Name | Trmt6 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 146 | KTEFAQDKYIKKKKK |
| 154 | YIKKKKKKYEAIITI |
Function
Substrate-binding subunit of tRNA (adenine-N1-)-methyltransferase, which catalyzes the formation of N1-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA
Protein Sequence
10
MELSAAEQPS
20
PQPPHLGDHC
30
IHDGDFVVLK
40
REDVFKAVQV
50
QRRKKVTFEK
60
QWFYLDNAIG
70
HSYGSTFEVS
80
SGGSLQLRKK
90
LEEPTSETKE
100
AGTDNRNIVD
110
DGKSQKLTQD
120
DIKALKDKGI
130
KGEEIVQQLI
140
ENSTTFRDKT
150
EFAQDKYIKK
160
KKKKYEAIIT
170
ILKPSTRILS
180
IMYYAREPGK
190
INHMRYDTLA
200
QMLTLGNIRA
210
GNKMIVMETC
220
SGLVLGAMME
230
RMGGFGSIIQ
240
LYPGDGPVRA
250
ATACFGFPKS
260
FLSGLHEFPL
270
NKVKSLLNGT
280
FSAEMLSSEP
290
KDSTPVKESN
300
GELEKEIAEQ
310
ADKDSIADGP
320
ESNAEQNPVD
330
IVPGDPESKE
340
PKEKGSKRDY
350
IQEKQRRQEE
360
QRKRHMEAAA
370
LLGERNADGL
380
IVASRFHPTP
390
LLLSLLDFVA
400
PSRPFVVYCQ
410
YKEPLLECYT
420
KLRERGGVIN
430
LRLSETWLRN
440
YQVLPDRSHP
450
KLLMSGGGGY
460
LLSGFTVVSD
470
SHRVDPSLKS
480
CASALDSPKT
490
EEPAAKKQKC
MESAS
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0031515 | tRNA (m1A) methyltransferase complex |
| Biological Process | GO:0006397 | mRNA processing |
| Biological Process | GO:0030488 | tRNA methylation |
Reference
[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.