Search Results
Overview
| Uniprot ID | D3ZX38 |
|---|---|
| Protein Name | Prefoldin subunit 1 |
| Gene Name | Pfdn1 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 83 | IHNQLLEKQKIAEEK |
Function
Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins
Protein Sequence
10
MAASVDLELK
20
KAFTELQAKV
30
IDTQQKVKLA
40
DIQIEQLNRT
50
KKHAHLTDTE
60
IMTLVDETNM
70
YEGVGRMFIL
80
QSKEVIHNQL
90
LEKQKIAEEK
100
IKELEQKKSY
110
LERSVKEAED
120
NIREMLMARR
AQ
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0016272 | prefoldin complex |
| Molecular Function | GO:0044183 | protein folding chaperone |
| Molecular Function | GO:0051082 | unfolded protein binding |
| Biological Process | GO:0006457 | protein folding |
Reference
[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.