Search Results
Overview
| Uniprot ID | D3ZZK8 |
|---|---|
| Protein Name | Protein FRG1 |
| Gene Name | Frg1 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 212 | CEINYVKKFQSFQDH |
| 220 | FQSFQDHKLKISKED |
| 236 | KILKKARKDGFLHET |
Function
Binds to mRNA in a sequence-independent manner. May play a role in regulation of pre-mRNA splicing or in the assembly of rRNA into ribosomal subunits. May be involved in mRNA transport. May be involved in epigenetic regulation of muscle differentiation through regulation of activity of the histone-lysine N-methyltransferase KMT5B
Protein Sequence
10
MAEYSYVKST
20
KLVLKGTKAK
30
SKKKKSKDKK
40
RKREEDEEAQ
50
LDIVGIWWTV
60
SNFGEISGTI
70
AIEMDKGAYI
80
HALDNGLFTL
90
GAPHREVDEG
100
PSPPEQFTAV
110
KLSDSRIALK
120
SGYGKYLGIN
130
SDGLVVGRSD
140
AIGPREQWEP
150
VFQDGKMALL
160
ASNSCFIRCN
170
EAGDIEAKNK
180
TAGEEEMIKI
190
RSCAEREAKK
200
KDDIAEEDKG
210
SVQQCEINYV
220
KKFQSFQDHK
230
LKISKEDSKI
240
LKKARKDGFL
250
HETLLDRRAK
LKADRYCK
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0015030 | Cajal body |
| Cellular Component | GO:0071013 | catalytic step 2 spliceosome |
| Cellular Component | GO:0005730 | nucleolus |
| Cellular Component | GO:0055120 | striated muscle dense body |
| Cellular Component | GO:0030018 | Z disc |
| Molecular Function | GO:0051015 | actin filament binding |
| Molecular Function | GO:0003723 | RNA binding |
| Biological Process | GO:0007517 | muscle organ development |
| Biological Process | GO:0006364 | rRNA processing |
Reference
[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.