Search Results

Overview

Uniprot IDD3ZZR5
Protein Name-
Gene NameSnrpa1
OrganismRattus norvegicus

Kla Sites from experimental identification

Position Flanking peptide
172 KRGAQLAKDIARRSK
179 KDIARRSKTFNPGAG
191 GAGLPTDKKKGGPSA

Function

Involved in pre-mRNA splicing as component of the spliceosome. Associated with sn-RNP U2, where it contributes to the binding of stem loop IV of U2 snRNA

Protein Sequence

10 MVKLTAELIE 20 QAAQYTNAVR 30 DRELDLRGYK 40 IPVIENLGAT 50 LDQFDAIDFS 60 DNEIRKLDGF 70 PLLRRLKTLL 80 VNNNRICRIG 90 EGLDQALPCL 100 TELILTNNSL 110 VELGDLDPLA 120 SLKSLTYLSI 130 LRNPVTNKKH 140 YRLYVIYKVP 150 QVRVLDFQKV 160 KLKERQEAEK 170 MFKGKRGAQL 180 AKDIARRSKT 190 FNPGAGLPTD 200 KKKGGPSAGD 210 VEAIKNAIAN 220 ASTLAEVERL 230 KGLLQSGQIP 240 GRERRSGPSD 250 EGEEEMEDGT VTNGS

Gene Ontology

Classification GO ID Description
Cellular Component GO:0071013 catalytic step 2 spliceosome
Cellular Component GO:0016604 nuclear body
Cellular Component GO:0016607 nuclear speck
Cellular Component GO:0005654 nucleoplasm
Cellular Component GO:0005634 nucleus
Cellular Component GO:0071014 post-mRNA release spliceosomal complex
Cellular Component GO:0071020 post-spliceosomal complex
Cellular Component GO:0071011 precatalytic spliceosome
Cellular Component GO:0005681 spliceosomal complex
Cellular Component GO:0005686 U2 snRNP
Cellular Component GO:0071006 U2-type catalytic step 1 spliceosome
Cellular Component GO:0071007 U2-type catalytic step 2 spliceosome
Cellular Component GO:0071005 U2-type precatalytic spliceosome
Cellular Component GO:0005684 U2-type spliceosomal complex
Molecular Function GO:0030620 U2 snRNA binding
Biological Process GO:0000398 mRNA splicing, via spliceosome
Biological Process GO:0007283 spermatogenesis

Reference

[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.