Search Results
Overview
| Uniprot ID | D4A3M8 |
|---|---|
| Protein Name | Cytoplasmic protein |
| Gene Name | Nck2 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 72 | GSLVKNLKDTLGLGK |
Function
No function data available.
Protein Sequence
10
MTEEVIVIAK
20
WDYTAQQDQE
30
LDIRKNERLW
40
LLDDSKTWWR
50
VRNAANRTGY
60
VPSNYVERKN
70
SLKKGSLVKN
80
LKDTLGLGKT
90
RRKPSARDAS
100
PTPSTDAEYP
110
ANGSGADRIY
120
DLNIPAFVKF
130
AYVAEREDEL
140
SLVKGSRVTV
150
MEKCSDGWWR
160
GSFNGQIGWF
170
PSNYVLEEAD
180
EAAAEAPSFL
190
SLRRGTALSN
200
GQGARVLHVV
210
QTLYPFSSVT
220
EEELSFEKGE
230
TMEVIEKPEN
240
DPEWWKCKNA
250
RGQVGLVPKN
260
YVVVLSDGPA
270
LHPTHTPQIS
280
YTGPSASGRF
290
AGREWYYGNV
300
TRHQAECALN
310
ERGVEGDFLI
320
RDSESSPSDF
330
SVSLKASGRN
340
KHFKVQLVDS
350
VYCIGQRRFH
360
SMDELVEHYK
370
KAPIFTSEHG
380
EKLYLVRALQ
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Molecular Function | GO:0035591 | signaling adaptor activity |
| Biological Process | GO:0007015 | actin filament organization |
| Biological Process | GO:0016477 | cell migration |
| Biological Process | GO:0060996 | dendritic spine development |
| Biological Process | GO:0048013 | ephrin receptor signaling pathway |
| Biological Process | GO:0001771 | immunological synapse formation |
| Biological Process | GO:0030032 | lamellipodium assembly |
| Biological Process | GO:1903898 | negative regulation of PERK-mediated unfolded protein response |
| Biological Process | GO:0000122 | negative regulation of transcription by RNA polymerase II |
| Biological Process | GO:0030838 | positive regulation of actin filament polymerization |
| Biological Process | GO:1902237 | positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway |
| Biological Process | GO:0042102 | positive regulation of T cell proliferation |
| Biological Process | GO:0045944 | positive regulation of transcription by RNA polymerase II |
| Biological Process | GO:0036493 | positive regulation of translation in response to endoplasmic reticulum stress |
| Biological Process | GO:0036491 | regulation of translation initiation in response to endoplasmic reticulum stress |
| Biological Process | GO:0034976 | response to endoplasmic reticulum stress |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005783 | endoplasmic reticulum |
| Cellular Component | GO:0014069 | postsynaptic density |
| Cellular Component | GO:0045202 | synapse |
| Cellular Component | GO:0012506 | vesicle membrane |
| Molecular Function | GO:0001784 | phosphotyrosine residue binding |
| Molecular Function | GO:0044877 | protein-containing complex binding |
| Molecular Function | GO:0030971 | receptor tyrosine kinase binding |
| Molecular Function | GO:0097110 | scaffold protein binding |
Reference
[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.