Search Results

Overview

Uniprot IDD4A579
Protein NameZinc finger and BTB domain-containing protein 7B
Gene NameZbtb7b
OrganismRattus norvegicus

Kla Sites from experimental identification

Position Flanking peptide
210 RRSRKPRKAFLQTKG
216 RKAFLQTKGARANHL

Function

No function data available.

Protein Sequence

10 MGSPEDDLIG 20 IPFPDHSSEL 30 LSCLNEQRQL 40 GHLCDLTIRT 50 QGLEYRTHRA 60 VLAACSHYFK 70 KLFTEGGGGT 80 VMGTGGGGTA 90 AGGAGAGVCE 100 LDFVGPEALG 110 ALLEFAYTAT 120 LTTSSANMPA 130 VLQAARLLEI 140 PCVIAACMEI 150 LQGSGLEAPS 160 PDEDDCERAR 170 QYLEAFATAT 180 TTASTSGMPN 190 GEDSPPQVPL 200 LPPPPPPPRP 210 VARRSRKPRK 220 AFLQTKGARA 230 NHLVPEAPTV 240 LTHPLAYEEE 250 EMVGRVGNSG 260 GSGLGDNYSP 270 PAGATSPAEG 280 PLNYEVFEGE 290 EEEEELVYPP 300 AYGLAQSNEP 310 SLSPEELGSD 320 EDPIDPDLMA 330 YLSSLHQDAL 340 APGLDGQDKL 350 VRKRRSQMPQ 360 ECPVCHKIIH 370 GAGKLPRHMR 380 THTGEKPFAC 390 EVCGVRFTRN 400 DKLKIHMRKH 410 TGERPYSCPH 420 CPARFLHSYD 430 LKNHMHLHTG 440 DRPYECHLCH 450 KAFAKEDHLQ 460 RHLKGQNCLE 470 VRTRRRRKDD 480 APPHYPPPST 490 TTSSPAGLDL 500 SNGHLDTFRL 510 SLARFWEQSA 520 TTGPPVTTQG 530 PPEEEEEEGT 540 PTTPQAESAM ESS

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005654 nucleoplasm
Cellular Component GO:0005634 nucleus
Molecular Function GO:0000987 cis-regulatory region sequence-specific DNA binding
Molecular Function GO:0003677 DNA binding
Molecular Function GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
Molecular Function GO:0003700 DNA-binding transcription factor activity
Molecular Function GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
Molecular Function GO:0001217 DNA-binding transcription repressor activity
Molecular Function GO:0042826 histone deacetylase binding
Molecular Function GO:0042802 identical protein binding
Molecular Function GO:0042803 protein homodimerization activity
Molecular Function GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
Molecular Function GO:1990837 sequence-specific double-stranded DNA binding
Molecular Function GO:0008270 zinc ion binding
Biological Process GO:1990845 adaptive thermogenesis
Biological Process GO:0006351 DNA-templated transcription
Biological Process GO:0007595 lactation
Biological Process GO:0043377 negative regulation of CD8-positive, alpha-beta T cell differentiation
Biological Process GO:0010629 negative regulation of gene expression
Biological Process GO:0051141 negative regulation of NK T cell proliferation
Biological Process GO:2000320 negative regulation of T-helper 17 cell differentiation
Biological Process GO:0000122 negative regulation of transcription by RNA polymerase II
Biological Process GO:0001865 NK T cell differentiation
Biological Process GO:0090336 positive regulation of brown fat cell differentiation
Biological Process GO:0043372 positive regulation of CD4-positive, alpha-beta T cell differentiation
Biological Process GO:0120162 positive regulation of cold-induced thermogenesis
Biological Process GO:0010628 positive regulation of gene expression
Biological Process GO:0046628 positive regulation of insulin receptor signaling pathway
Biological Process GO:0032740 positive regulation of interleukin-17 production
Biological Process GO:2000640 positive regulation of SREBP signaling pathway
Biological Process GO:0045944 positive regulation of transcription by RNA polymerase II
Biological Process GO:0043370 regulation of CD4-positive, alpha-beta T cell differentiation
Biological Process GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation
Biological Process GO:0010468 regulation of gene expression
Biological Process GO:0006357 regulation of transcription by RNA polymerase II
Biological Process GO:0032868 response to insulin

Reference

[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.