Search Results
Overview
| Uniprot ID | D4A586 |
|---|---|
| Protein Name | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related |
| Gene Name | Hmg20b |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 154 | TEKIQENKIKKEDSS |
| 31 | GAFVVAVKQERSEGP |
Function
Required for correct progression through G2 phase of the cell cycle and entry into mitosis. Required for RCOR1/CoREST mediated repression of neuronal specific gene promoters
Protein Sequence
10
MSHGPRQPGA
20
ATAPAGGKTP
30
GQHGAFVVAV
40
KQERSEGPRA
50
GEKGPQEEEP
60
VKKRGWPKGK
70
KRKKILPNGP
80
KAPVTGYVRF
90
LNERREQIRT
100
RHPDLPFPEI
110
TKMLGAEWSK
120
LQPAEKQRYL
130
DEAEKEKQQY
140
LKELWAYQQS
150
EAYKVCTEKI
160
QENKIKKEDS
170
SSGLMNTLLN
180
GHKGVDCGDG
190
FSTFDVPIFT
200
EEFLDQNKAR
210
EAELRRLRKM
220
NVAFEEQNAV
230
LQRHTQSMNS
240
ARERLEQELA
250
LEERRTLALQ
260
QQLQAVRQAL
270
TASFASLPVP
280
GAQPRPQLWA
290
RPQPRARPQD
300
VLLGPAPIPR
310
QAPLPQYLSH
320
LPDADLPVAR
330
TGETPTLGTL
340
DFYMARLHGA
350
IERDPAQHER
360
LIARVKEILA
RVASEHL
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0003677 | DNA binding |
| Biological Process | GO:0033234 | negative regulation of protein sumoylation |
| Biological Process | GO:0045666 | positive regulation of neuron differentiation |
| Biological Process | GO:0010468 | regulation of gene expression |
| Biological Process | GO:0035914 | skeletal muscle cell differentiation |
Reference
[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.