Search Results
Overview
| Uniprot ID | D4A8G7 |
|---|---|
| Protein Name | SNW domain-containing protein 1 |
| Gene Name | Snw1 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 153 | IQVDPEGKIKYDAIA |
Function
Involved in pre-mRNA splicing
Protein Sequence
10
MVPVPTRQAA
20
TIPTKRTTRP
30
RVPFGQSACA
40
VSIFHSVPRS
50
RARIAPRRCG
60
LRRKKRKKMA
70
LTSFLPAPTQ
80
LSQDQLEAEE
90
RARSQRSRQT
100
SLVSSRREPP
110
PYGYRKGWIP
120
RLLEDFGDGG
130
AFPEIHVAQY
140
PLDMGRKKKM
150
SNALAIQVDP
160
EGKIKYDAIA
170
RQGQSKDKVI
180
YSKYTDLVPK
190
EVMNADDPDL
200
QRPDEEAIKE
210
ITEKTRVALE
220
KSVSQKVAAA
230
MPVRAADKLA
240
PAQYIRYTPS
250
QQGVAFNSGA
260
KQRVIRMVEM
270
QKDPMEPPRF
280
KINKKIPRGP
290
PSPPAPVMHS
300
PSRKMTVKEQ
310
QEWKIPPCIS
320
NWKNAKGYTI
330
PLDKRLAADG
340
RGLQTVHINE
350
NFAKLAEALY
360
IADRKAREAV
370
EMRAQVERKM
380
AQKEKEKHEE
390
KLREMAQKAR
400
ERRAGIKTHV
410
EKEDGEARER
420
DEIRHDRRKE
430
RQHDRNLSRA
440
APDKRSKLQR
450
NENRDISEVI
460
ALGVPNPRTS
470
NEVQYDQRLF
480
NQSKGMDSGF
490
AGGEDEIYNV
500
YDQAWRGGKD
510
MAQSIYRPSK
520
NLDKDMYGDD
530
LETRIKTNRF
540
VPDKEFSGSD
550
GRKRGREGPV
560
QFEEDPFGLD
570
KFLEEAKQHG
580
GSKRPSDSSR
590
PKEHEHEGKK
RRKE
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0071013 | catalytic step 2 spliceosome |
| Cellular Component | GO:0000785 | chromatin |
| Cellular Component | GO:0008024 | cyclin/CDK positive transcription elongation factor complex |
| Cellular Component | GO:0016363 | nuclear matrix |
| Cellular Component | GO:0016607 | nuclear speck |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0071014 | post-mRNA release spliceosomal complex |
| Cellular Component | GO:0071020 | post-spliceosomal complex |
| Cellular Component | GO:0071141 | SMAD protein complex |
| Cellular Component | GO:0005681 | spliceosomal complex |
| Cellular Component | GO:0071018 | U12-type catalytic step 2 spliceosome |
| Cellular Component | GO:0071006 | U2-type catalytic step 1 spliceosome |
| Cellular Component | GO:0071007 | U2-type catalytic step 2 spliceosome |
| Molecular Function | GO:0019899 | enzyme binding |
| Molecular Function | GO:0005112 | Notch binding |
| Molecular Function | GO:0050681 | nuclear androgen receptor binding |
| Molecular Function | GO:0016922 | nuclear receptor binding |
| Molecular Function | GO:0042974 | nuclear retinoic acid receptor binding |
| Molecular Function | GO:0042809 | nuclear vitamin D receptor binding |
| Molecular Function | GO:0046332 | SMAD binding |
| Molecular Function | GO:0003713 | transcription coactivator activity |
| Molecular Function | GO:0003714 | transcription corepressor activity |
| Biological Process | GO:0071300 | cellular response to retinoic acid |
| Biological Process | GO:0043923 | host-mediated activation of viral transcription |
| Biological Process | GO:0042771 | intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator |
| Biological Process | GO:0000398 | mRNA splicing, via spliceosome |
| Biological Process | GO:0045892 | negative regulation of DNA-templated transcription |
| Biological Process | GO:0000122 | negative regulation of transcription by RNA polymerase II |
| Biological Process | GO:0048026 | positive regulation of mRNA splicing, via spliceosome |
| Biological Process | GO:0050769 | positive regulation of neurogenesis |
| Biological Process | GO:0045944 | positive regulation of transcription by RNA polymerase II |
| Biological Process | GO:0030511 | positive regulation of transforming growth factor beta receptor signaling pathway |
| Biological Process | GO:0070564 | positive regulation of vitamin D receptor signaling pathway |
| Biological Process | GO:0048385 | regulation of retinoic acid receptor signaling pathway |
| Biological Process | GO:0070562 | regulation of vitamin D receptor signaling pathway |
| Biological Process | GO:0048384 | retinoic acid receptor signaling pathway |
| Biological Process | GO:0014010 | Schwann cell proliferation |
| Biological Process | GO:0035914 | skeletal muscle cell differentiation |
Reference
[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.