Search Results
Overview
| Uniprot ID | D4A986 |
|---|---|
| Protein Name | - |
| Gene Name | Mbd2 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 168 | KKEEVIRKSGLSAGK |
| 175 | KSGLSAGKSDVYYFS |
| 186 | YYFSPSGKKFRSKPQ |
| 191 | SGKKFRSKPQLARYL |
| 213 | SFDFRTGKMMPSKLQ |
| 218 | TGKMMPSKLQKNKQR |
| 383 | RVQQVRKKLEEALMA |
Function
No function data available.
Protein Sequence
10
MRAHPGGGRC
20
CPEQEEGESA
30
AGGSGAGGDS
40
AIEQGGQGSA
50
LAPSPVSGVR
60
REGARGGGRG
70
RGRWKQAARG
80
GGVCGRGRGR
90
GRGRGRGRGR
100
GRGRGRPQSG
110
GSGLGGDGGA
120
GGCGVGSSGG
130
VAPRRDPVPF
140
PSGSSGPGPR
150
GPRATESGKR
160
MDCPALPPGW
170
KKEEVIRKSG
180
LSAGKSDVYY
190
FSPSGKKFRS
200
KPQLARYLGN
210
AVDLSSFDFR
220
TGKMMPSKLQ
230
KNKQRLRNDP
240
LNQNKGKPDL
250
NTTLPIRQTA
260
SIFKQPVTKV
270
TNHPNNKVKS
280
DPQRMNEQPR
290
QLFWEKRLQG
300
LSASDVTEQI
310
IKTMELPKGL
320
QGVGPGSNDE
330
TLLSAVASAL
340
HTSSAPITGQ
350
VSAAVEKNPA
360
VWLNTSQPLC
370
KAFIVTDDDI
380
RKQEERVQQV
390
RKKLEEALMA
400
DILSRAVDTE
410
EVDIDMDSGD
EE
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0016581 | NuRD complex |
| Molecular Function | GO:0070742 | C2H2 zinc finger domain binding |
| Molecular Function | GO:0003682 | chromatin binding |
| Molecular Function | GO:0003677 | DNA binding |
| Molecular Function | GO:0008327 | methyl-CpG binding |
| Molecular Function | GO:0060090 | molecular adaptor activity |
| Molecular Function | GO:0003729 | mRNA binding |
| Molecular Function | GO:0019904 | protein domain specific binding |
| Molecular Function | GO:0035197 | siRNA binding |
| Biological Process | GO:1904015 | cellular response to serotonin |
| Biological Process | GO:0006338 | chromatin remodeling |
| Biological Process | GO:0006346 | DNA methylation-dependent constitutive heterochromatin formation |
| Biological Process | GO:0006351 | DNA-templated transcription |
| Biological Process | GO:0048568 | embryonic organ development |
| Biological Process | GO:0040029 | epigenetic regulation of gene expression |
| Biological Process | GO:0042711 | maternal behavior |
| Biological Process | GO:0000122 | negative regulation of transcription by RNA polymerase II |
| Biological Process | GO:0030177 | positive regulation of Wnt signaling pathway |
| Biological Process | GO:0065003 | protein-containing complex assembly |
| Biological Process | GO:0042127 | regulation of cell population proliferation |
| Biological Process | GO:0006357 | regulation of transcription by RNA polymerase II |
| Biological Process | GO:1903925 | response to bisphenol A |
| Biological Process | GO:0032355 | response to estradiol |
| Biological Process | GO:0009612 | response to mechanical stimulus |
| Biological Process | GO:0031667 | response to nutrient levels |
| Biological Process | GO:0003229 | ventricular cardiac muscle tissue development |
| Cellular Component | GO:0000785 | chromatin |
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0000792 | heterochromatin |
| Cellular Component | GO:0000118 | histone deacetylase complex |
Reference
[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.
[2] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.