Search Results
Overview
| Uniprot ID | D4A9L2 |
|---|---|
| Protein Name | Serine/arginine-rich splicing factor 1 |
| Gene Name | Srsf1 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 30 | LPPDIRTKDIEDVFY |
Function
No function data available.
Protein Sequence
10
MSGGGVIRGP
20
AGNNDCRIYV
30
GNLPPDIRTK
40
DIEDVFYKYG
50
AIRDIDLKNR
60
RGGPPFAFVE
70
FEDPRDAEDA
80
VYGRDGYDYD
90
GYRLRVEFPR
100
SGRGTGRGGG
110
GGGGGGAPRG
120
RYGPPSRRSE
130
NRVVVSGLPP
140
SGSWQDLKDH
150
MREAGDVCYA
160
DVYRDGTGVV
170
EFVRKEDMTY
180
AVRKLDNTKF
190
RSHEGETAYI
200
RVKVDGPRSP
210
SYGRSRSRSR
220
SRSRSRSRSN
230
SRSRSYSPRR
240
SRGSPRYSPR
HSRSRSRT
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0071013 | catalytic step 2 spliceosome |
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0035145 | exon-exon junction complex |
| Cellular Component | GO:0005635 | nuclear envelope |
| Cellular Component | GO:0016607 | nuclear speck |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0044547 | DNA topoisomerase binding |
| Molecular Function | GO:0003729 | mRNA binding |
| Molecular Function | GO:0043422 | protein kinase B binding |
| Molecular Function | GO:0003723 | RNA binding |
| Molecular Function | GO:0050733 | RS domain binding |
| Biological Process | GO:0000380 | alternative mRNA splicing, via spliceosome |
| Biological Process | GO:0060048 | cardiac muscle contraction |
| Biological Process | GO:0097398 | cellular response to interleukin-17 |
| Biological Process | GO:0001701 | in utero embryonic development |
| Biological Process | GO:0097400 | interleukin-17-mediated signaling pathway |
| Biological Process | GO:0097421 | liver regeneration |
| Biological Process | GO:0000395 | mRNA 5'-splice site recognition |
| Biological Process | GO:0048255 | mRNA stabilization |
| Biological Process | GO:0048709 | oligodendrocyte differentiation |
| Biological Process | GO:0033120 | positive regulation of RNA splicing |
| Biological Process | GO:0034504 | protein localization to nucleus |
| Biological Process | GO:0110012 | protein localization to P-body |
| Biological Process | GO:0000381 | regulation of alternative mRNA splicing, via spliceosome |
| Biological Process | GO:0043484 | regulation of RNA splicing |
| Biological Process | GO:0008380 | RNA splicing |
Reference
[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.