Search Results
Overview
| Uniprot ID | D4AAJ3 |
|---|---|
| Protein Name | 40S ribosomal protein S12 |
| Gene Name | Rps12l5 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 112 | GCSCIVVKDYGKESQ |
Function
Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. Subunit of the 40S ribosomal complex
Protein Sequence
10
MAEGDIAAGG
20
VIDINTALQE
30
VLKTAFIHDA
40
LACGIREAAK
50
ALDKCQAHLC
60
VLASNCDEPM
70
YVKLVEALCA
80
EHQINLMKVD
90
DNKKLGEWVG
100
PCKIDLEGKP
110
LKVVGCSCIV
120
VKDYGKESQD
130
KDVIKEYFKC
KK
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0022627 | cytosolic small ribosomal subunit |
| Molecular Function | GO:0003735 | structural constituent of ribosome |
| Biological Process | GO:1990145 | maintenance of translational fidelity |
| Biological Process | GO:0042274 | ribosomal small subunit biogenesis |
Reference
[1] Yao Y, Bade R, Li G, Zhang A, Zhao H et al.. Global-Scale Profiling of Differential Expressed Lysine-Lactylated Proteins in the Cerebral Endothelium of Cerebral Ischemia-Reperfusion Injury Rats.. Cell Mol Neurobiol 43(5):1989-2004. 2023 Jul. PMID: 36030297.