Search Results
Overview
| Uniprot ID | D4ACD8 |
|---|---|
| Protein Name | Homeobox protein Hox-D10 |
| Gene Name | Hoxd10 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 192 | MYSDKRNKLISAEVP |
Function
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis
Protein Sequence
10
MSLLSVLPRP
20
AGRAVEHVTC
30
KEAAAQGHFQ
40
ISLAWLSCGR
50
QRHPQLHREC
60
FPSDVSLQRT
70
QSLFFKFLPK
80
MSFPNSSPAA
90
NTFLVDSLIS
100
ACRSDSFYSS
110
SASMYMPPPS
120
ADMGTYGMQT
130
CGLLPSLAKR
140
EVNHQNMGMN
150
VHPYIPQVDS
160
WTDPNRSCRI
170
EQPVTQQVPT
180
CSFTANIKEE
190
SNCCMYSDKR
200
NKLISAEVPS
210
YQRLVPESCP
220
VENPEVPVPG
230
YFRLSQTYAT
240
GKTQEYNNNP
250
EGSSTVMLQL
260
NPRGAAKPQL
270
SAAQLQMEKK
280
MNETASGQEP
290
TKVSQVESPE
300
AKGGLPEERS
310
CLAEVSVSSP
320
EVQEKESKEE
330
IKSDTPTSNW
340
LTAKSGRKKR
350
CPYTKHQTLE
360
LEKEFLFNMY
370
LTRERRLEIS
380
KSVNLTDRQV
390
KIWFQNRRMK
400
LKKMSRENRI
410
RELTANLTFS
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0003682 | chromatin binding |
| Molecular Function | GO:0003677 | DNA binding |
| Molecular Function | GO:0001228 | DNA-binding transcription activator activity, RNA polymerase II-specific |
| Molecular Function | GO:0003700 | DNA-binding transcription factor activity |
| Molecular Function | GO:0000981 | DNA-binding transcription factor activity, RNA polymerase II-specific |
| Molecular Function | GO:0000978 | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| Molecular Function | GO:0000977 | RNA polymerase II transcription regulatory region sequence-specific DNA binding |
| Molecular Function | GO:1990837 | sequence-specific double-stranded DNA binding |
| Biological Process | GO:0008344 | adult locomotory behavior |
| Biological Process | GO:0009952 | anterior/posterior pattern specification |
| Biological Process | GO:0006351 | DNA-templated transcription |
| Biological Process | GO:0030326 | embryonic limb morphogenesis |
| Biological Process | GO:0048704 | embryonic skeletal system morphogenesis |
| Biological Process | GO:0035136 | forelimb morphogenesis |
| Biological Process | GO:0035137 | hindlimb morphogenesis |
| Biological Process | GO:0050905 | neuromuscular process |
| Biological Process | GO:0048935 | peripheral nervous system neuron development |
| Biological Process | GO:0045944 | positive regulation of transcription by RNA polymerase II |
| Biological Process | GO:0009954 | proximal/distal pattern formation |
| Biological Process | GO:0010468 | regulation of gene expression |
| Biological Process | GO:0006357 | regulation of transcription by RNA polymerase II |
| Biological Process | GO:0007338 | single fertilization |
| Biological Process | GO:0007519 | skeletal muscle tissue development |
| Biological Process | GO:0001501 | skeletal system development |
| Biological Process | GO:0021520 | spinal cord motor neuron cell fate specification |
Reference
[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.