Search Results
Overview
| Uniprot ID | D4AE08 |
|---|---|
| Protein Name | Protein Abitram |
| Gene Name | Abitram |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 92 | NCSRLQNKVSGKFKR |
Function
Actin-binding protein that regulates actin polymerization, filopodia dynamics and increases the branching of proximal dendrites of developing neurons
Protein Sequence
10
MEELPCPEAG
20
VVAPEVVMST
30
EPPAPSLVDR
40
YFTRWYKADV
50
KGKPCEDHCI
60
LQHSNRICVI
70
TLAGSHPVLQ
80
SGKTIKSISY
90
QISNNCSRLQ
100
NKVSGKFKRG
110
AQFLTELAPL
120
CKIYCSDGEE
130
YTISSCIRGR
140
LMEVNENILH
150
QPSLLQEKPS
160
TEGYIAVVLP
170
KFEESKSITE
180
GLLTQQQYEE
190
VLVKRTDATT
VTS
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0030425 | dendrite |
| Cellular Component | GO:0032433 | filopodium tip |
| Cellular Component | GO:0030426 | growth cone |
| Cellular Component | GO:0030027 | lamellipodium |
| Cellular Component | GO:0016607 | nuclear speck |
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0051015 | actin filament binding |
| Molecular Function | GO:0003785 | actin monomer binding |
| Biological Process | GO:0048813 | dendrite morphogenesis |
| Biological Process | GO:0030833 | regulation of actin filament polymerization |
| Biological Process | GO:0051489 | regulation of filopodium assembly |
Reference
[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.