Search Results
Overview
| Uniprot ID | E9PT29 |
|---|---|
| Protein Name | RNA helicase |
| Gene Name | Ddx17 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 30 | GSGLPPKKFGNPGER |
| 42 | GERLRKKKWDLSELP |
Function
No function data available.
Protein Sequence
10
MRGGGFGDRD
20
RDRDRGGFGA
30
RGGSGLPPKK
40
FGNPGERLRK
50
KKWDLSELPK
60
FEKNFYVEHP
70
EVARLTPYEV
80
DELRRKKEIT
90
VRGGDVCPKP
100
VFAFHHANFP
110
QYVMDVLMDQ
120
HFTEPTPIQC
130
QGFPLALSGR
140
DMVGIAQTGS
150
GKTLAYLLPA
160
IVHINHQPYL
170
ERGDGPICLV
180
LAPTRELAQQ
190
VQQVADDYGK
200
CSRLKSTCIY
210
GGAPKGPQIR
220
DLERGVEICI
230
ATPGRLIDFL
240
ESGKTNLRRC
250
TYLVLDEADR
260
MLDMGFEPQI
270
RKIVDQIRPD
280
RQTLMWSATW
290
PKEVRQLAED
300
FLRDYTQINV
310
GNLELSANHN
320
ILQIVDVCME
330
SEKDHKLIQL
340
MEEIMAEKEN
350
KTIIFVETKR
360
RCDDLTRRMR
370
RDGWPAMCIH
380
GDKSQPERDW
390
VLNEFRSGKA
400
PILIATDVAS
410
RGLDVEDVKF
420
VINYDYPNSS
430
EDYVHRIGRT
440
ARSTNKGTAY
450
TFFTPGNLKQ
460
ARELIKVLEE
470
ANQAINPKLM
480
QLVDHRGGGG
490
GGGKGGRSRY
500
RTTSSANNPN
510
LMYQDECDRR
520
LRGVKDGGRR
530
DSTSYRDRSE
540
TDRASYANGS
550
GYGSPNSAFG
560
AQAGQYTYAQ
570
GTYGAAAYGT
580
SGYTAQEYAA
590
GTYGASSTTS
600
TGRSSQSSSQ
610
QFSGIGRSGQ
620
QPQPLMSQQF
630
AQPPGATNMI
640
GYMGQTAYQY
650
PPPPPPPPPS
RK
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0016607 | nuclear speck |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:1990904 | ribonucleoprotein complex |
| Molecular Function | GO:0005524 | ATP binding |
| Molecular Function | GO:0031490 | chromatin DNA binding |
| Molecular Function | GO:0016787 | hydrolase activity |
| Molecular Function | GO:0106222 | lncRNA binding |
| Molecular Function | GO:0003729 | mRNA binding |
| Molecular Function | GO:0003724 | RNA helicase activity |
| Molecular Function | GO:0003713 | transcription coactivator activity |
| Biological Process | GO:0000380 | alternative mRNA splicing, via spliceosome |
| Biological Process | GO:0030521 | androgen receptor signaling pathway |
| Biological Process | GO:0001837 | epithelial to mesenchymal transition |
| Biological Process | GO:0030520 | estrogen receptor signaling pathway |
| Biological Process | GO:0010467 | gene expression |
| Biological Process | GO:0010586 | miRNA metabolic process |
| Biological Process | GO:0061614 | miRNA transcription |
| Biological Process | GO:0045445 | myoblast differentiation |
| Biological Process | GO:0045944 | positive regulation of transcription by RNA polymerase II |
| Biological Process | GO:0000381 | regulation of alternative mRNA splicing, via spliceosome |
| Biological Process | GO:2001014 | regulation of skeletal muscle cell differentiation |
| Biological Process | GO:0006357 | regulation of transcription by RNA polymerase II |
Reference
[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.
[2] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.