Search Results

Overview

Uniprot ID	E9PT82
Protein Name	Striatin-3
Gene Name	Strn3
Organism	Rattus norvegicus

Kla Sites from experimental identification

Position	Flanking peptide
430	QKTVPAKKSASLDVE

Function

Calmodulin-binding scaffolding protein which is the center of the striatin-interacting phosphatase and kinase (STRIPAK) complexes. STRIPAK complexes have critical roles in protein (de)phosphorylation and are regulators of multiple signaling pathways including Hippo, MAPK, nuclear receptor and cytoskeleton remodeling. Different types of STRIPAK complexes are involved in a variety of biological processes such as cell growth, differentiation, apoptosis, metabolism and immune regulation

Protein Sequence

10 MDELAGGGGG 20 QGMAVPPRPQ 30 QGPGGNLSLP 40 PGANGAPGGG 50 GPPAAETAGP 60 PAGPELSRPQ 70 QYTIPGILHY 80 IQHEWARFEM 90 ERAHWEVERA 100 ELQARIAFLQ 110 GERKGQENLK 120 KDLVRRIKML 130 EYALKQERAK 140 YHKLKYGTEL 150 NQGDLKMPTF 160 ESEETKDAEA 170 PPAQNSQLTW 180 KQGRQLLRQY 190 LQEVGYTDTI 200 LDVRSQRVRS 210 LLGLSNSEPN 220 GSIEAKNLEQ 230 ILNGGESPKQ 240 KGQEIKRPSG 250 DVLETFNFLE 260 NADDSDEEEN 270 DMIEGIPEGK 280 DKLRIHKHKI 290 GNEGLAADLT 300 DDPDTEEALK 310 EFDFLVTAED 320 GEGAGEARSS 330 GDGTEWAEPI 340 TFPSGGGKSF 350 IMGSDDVLLS 360 VLGLGDLADL 370 TVTNDADYSY 380 DLPANKDALR 390 KTWNPKYTLR 400 SHFDGVRALA 410 FHPVEPVLVT 420 ASEDHTLKLW 430 NLQKTVPAKK 440 SASLDVEPIY 450 TFRAHIGPVL 460 SLAISSNGEQ 470 CFSGGIDATI 480 QWWNMPSPNV 490 DPYDTYESHV 500 LAGTLVAHTD 510 AVWGLAYSGI 520 KNQLLSCSAD 530 GTIRLWNPQE 540 KLPCICTYNG 550 DKEHGIPTSV 560 DFIGCDPAHM 570 VTSFNTGSAI 580 IYDLETSQSL 590 VMLSSQVDSG 600 LQSSNHINRV 610 VSHPTLPVTI 620 TAHEDRHIKF 630 FDNKTGKMIH 640 SMVAHLDAVT 650 SLAVDPNGIY 660 LMSGSHDCSI 670 RLWNLDSKTC 680 VQEITAHRKK 690 LDESIYDVAF 700 HPSKAYIASA 710 GADALAKVFV

Gene Ontology

Classification	GO ID	Description
Cellular Component	GO:0005737	cytoplasm
Cellular Component	GO:0016020	membrane
Molecular Function	GO:0005516	calmodulin binding

Reference

[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.