Search Results
Overview
| Uniprot ID | E9Q5G3 |
|---|---|
| Protein Name | Kinesin-like protein KIF23 |
| Gene Name | Kif23 |
| Organism | Mus musculus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 600 | ELESQNQKLQRQFSD |
| 608 | LQRQFSDKRRLEARL |
Function
Component of the centralspindlin complex that serves as a microtubule-dependent and Rho-mediated signaling required for the myosin contractile ring formation during the cell cycle cytokinesis. Essential for cytokinesis in Rho-mediated signaling. Required for the localization of ECT2 to the central spindle. Plus-end-directed motor enzyme that moves antiparallel microtubules in vitro (By similarity)
Protein Sequence
10
MKSAKAKTVR
20
KPVIKKGSQT
30
NLKDPVGVYC
40
RVRPLSFPDQ
50
ECCVEVINST
60
TLQLHTPEGY
70
RLNRNGDYKE
80
TQYSFKRVFG
90
THTTQKELFD
100
VVANPLVDDL
110
IHGKNGLLFT
120
YGVTGSGKTY
130
TMTGSPGSGG
140
LLPRCLNMIF
150
NSIGSFQAKR
160
YVFKSNDRNS
170
MEIQCEVDAL
180
LERQKREALP
190
IPKTPSSKRQ
200
ADPEFADMIN
210
VQEFCKAEEV
220
DEDSVYGVFV
230
SYIEIYNNYI
240
YDLLEEVQFD
250
PIKPKLPQSK
260
TLREDKNHNM
270
YVAGCTEVEV
280
KSTEEAFEVF
290
WRGQKKRRIA
300
NTHLNRESSR
310
SHSVFSIKLV
320
QAPLDADGDN
330
VLQEKEQITI
340
SQLSLVDLAG
350
SERTNRTKAE
360
GNRLREAGNI
370
NQSLMTLRTC
380
MEVLRENQTY
390
GTNKMVPYRD
400
SKLTHLFKNY
410
FDGEGKVRMI
420
VCVNPKAEDY
430
EESLQVMRFA
440
EVTQEVEVAR
450
PVDKVICGLT
460
PGRRYRNLPR
470
GGPVGDEPLV
480
PEVILQSFPP
490
LPPCKLLDIN
500
DEETLPKLAD
510
TLEKRHHLRQ
520
LMTEDLNKKC
530
LAFKALLKEF
540
DNSLSNKENY
550
VQEKLNEREK
560
VISGQKLEIE
570
RLEKKNKTLE
580
YKIEILEKTT
590
TIYEEDKRNL
600
QQELESQNQK
610
LQRQFSDKRR
620
LEARLQGMVT
630
ETSMKWQKEC
640
ERRVAATQLE
650
MQNKLWVKDE
660
KLKQLKAIVT
670
EPKPEKPERP
680
SRERDREKII
690
PRSVSPSPLP
700
LSSNNIAQIS
710
NGQQLMSQPQ
720
LHRRSNSCSS
730
ISVASCISEW
740
EQKLSPFSTP
750
VNVTSLARHR
760
QQEPGQSKTC
770
IVSDRRRGMC
780
WTEGREMVPT
790
FSSEIGVEED
800
HCRRNTPIPV
810
RHRRSRSAGS
820
RWVDHKPASN
830
VQTETVMQPH
840
VPHAITVSVA
850
NEKALAKCEK
860
YMLTHQELAS
870
DGEIQTKVIK
880
GDVYKTRGGG
890
QSVQFTDIET
900
LKQELPTGSR
910
KRRSSTLAPA
920
QPDGTESEWT
930
DVETRCSVAV
940
EMRAGSQLGP
950
GYQHHAQPKR
KKP
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0097149 | centralspindlin complex |
| Cellular Component | GO:0005813 | centrosome |
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0090543 | Flemming body |
| Cellular Component | GO:0045171 | intercellular bridge |
| Cellular Component | GO:0005871 | kinesin complex |
| Cellular Component | GO:0005874 | microtubule |
| Cellular Component | GO:0030496 | midbody |
| Cellular Component | GO:0072686 | mitotic spindle |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0097227 | sperm annulus |
| Cellular Component | GO:0097225 | sperm midpiece |
| Cellular Component | GO:0097228 | sperm principal piece |
| Cellular Component | GO:0005819 | spindle |
| Molecular Function | GO:0005524 | ATP binding |
| Molecular Function | GO:0016887 | ATP hydrolysis activity |
| Molecular Function | GO:0008017 | microtubule binding |
| Molecular Function | GO:0003777 | microtubule motor activity |
| Biological Process | GO:0007018 | microtubule-based movement |
| Biological Process | GO:0000281 | mitotic cytokinesis |
| Biological Process | GO:0051256 | mitotic spindle midzone assembly |
| Biological Process | GO:0032467 | positive regulation of cytokinesis |
Reference
[1] Chang J, Wu W, Qian P, Lu Z, He X et al.. Multi-omics study on the effect of moderate-intensity exercise on protein lactylation in mouse muscle tissue.. Front Cell Dev Biol 12:1472338. 2024. PMID: 39935788.