Search Results
Overview
| Uniprot ID | F1LMW7 |
|---|---|
| Protein Name | Myristoylated alanine-rich C-kinase substrate |
| Gene Name | Marcks |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 11 | QFSKTAAKGEAAAER |
| 145 | SPSSETPKKKKKRFS |
| 158 | FSFKKSFKLSGFSFK |
| 165 | KLSGFSFKKSKKEAG |
| 169 | FSFKKSKKEAGEGAE |
Function
No function data available.
Protein Sequence
10
MGAQFSKTAA
20
KGEAAAERPG
30
EAAVASSPSK
40
ANGQENGHVK
50
VNGDASPAAA
60
EPGAKEELQA
70
NGSAPAADKE
80
EPASGGAATP
90
AAADKDEAAA
100
APESGAATAD
110
KEAAEAEPAE
120
PGSPSAETEG
130
ASASSTSSPK
140
AEDGAAPSPS
150
SETPKKKKKR
160
FSFKKSFKLS
170
GFSFKKSKKE
180
AGEGAEAEGA
190
TADGAKDEAA
200
AAAGGDAAAA
210
PGEQAGGAGA
220
EGAEGGESRE
230
AEAAEPEQPE
240
QPEQPAAEEP
250
RAEEPSEAVG
260
EKAEEPAPGA
270
TADDAPSAAG
280
PEQEAPAATD
290
EPAASAAPSA
300
SPEPQPECSP
EAPPAPVAE
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0032432 | actin filament bundle |
| Cellular Component | GO:0005938 | cell cortex |
| Cellular Component | GO:0005813 | centrosome |
| Cellular Component | GO:0042585 | germinal vesicle |
| Cellular Component | GO:0005886 | plasma membrane |
| Molecular Function | GO:0051015 | actin filament binding |
| Molecular Function | GO:0005516 | calmodulin binding |
| Molecular Function | GO:0042802 | identical protein binding |
| Molecular Function | GO:0005080 | protein kinase C binding |
| Biological Process | GO:0051764 | actin crosslink formation |
| Biological Process | GO:0051017 | actin filament bundle assembly |
| Biological Process | GO:0006915 | apoptotic process |
| Biological Process | GO:0007005 | mitochondrion organization |
| Biological Process | GO:0021915 | neural tube development |
| Biological Process | GO:0022008 | neurogenesis |
| Biological Process | GO:0034976 | response to endoplasmic reticulum stress |
Reference
[1] Yao Y, Bade R, Li G, Zhang A, Zhao H et al.. Global-Scale Profiling of Differential Expressed Lysine-Lactylated Proteins in the Cerebral Endothelium of Cerebral Ischemia-Reperfusion Injury Rats.. Cell Mol Neurobiol 43(5):1989-2004. 2023 Jul. PMID: 36030297.
[2] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.
[3] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.