Search Results
Overview
| Uniprot ID | F1LP05 |
|---|---|
| Protein Name | ATP synthase subunit alpha |
| Gene Name | Atp5f1a |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 161 | LGNAIDGKGPVGSKI |
| 167 | GKGPVGSKIRRRVGL |
| 230 | IDTIINQKRFNDGTD |
| 239 | FNDGTDEKKKLYCIY |
| 261 | STVAQLVKRLTDADA |
| 427 | AAQTRAMKQVAGTMK |
| 498 | GVRGYLDKLEPSKIT |
| 531 | GNIRSDGKISEQSDA |
| 539 | ISEQSDAKLKEIVTN |
Function
Produces ATP from ADP in the presence of a proton gradient across the membrane
Protein Sequence
10
MLSVRIAAAV
20
ARALPRRAGL
30
VSKNALGSSF
40
VGTRNLHASN
50
TRLQKTGTAE
60
MSSILEERIL
70
GADTSVDLEE
80
TGRVLSIGDG
90
IARVHGLRNV
100
QAEEMVEFSS
110
GLKGMSLNLE
120
PDNVGVVVFG
130
NDKLIKEGDI
140
VKRTGAIVDV
150
PVGDELLGRV
160
VDALGNAIDG
170
KGPVGSKIRR
180
RVGLKAPGII
190
PRISVREPMQ
200
TGIKAVDSLV
210
PIGRGQRELI
220
IGDRQTGKTS
230
IAIDTIINQK
240
RFNDGTDEKK
250
KLYCIYVAIG
260
QKRSTVAQLV
270
KRLTDADAMK
280
YTIVVSATAS
290
DAAPLQYLAP
300
YSGCSMGEYF
310
RDNGKHALII
320
YDDLSKQAVA
330
YRQMSLLLRR
340
PPGREAYPGD
350
VFYLHSRLLE
360
RAAKMNDSFG
370
GGSLTALPVI
380
ETQAGDVSAY
390
IPTNVISITD
400
GQIFLETELF
410
YKGIRPAINV
420
GLSVSRVGSA
430
AQTRAMKQVA
440
GTMKLELAQY
450
REVAAFAQFG
460
SDLDAATQQL
470
LSRGVRLTEL
480
LKQGQYSPMA
490
IEEQVAVIYA
500
GVRGYLDKLE
510
PSKITKFESA
520
FLSHVVSQHQ
530
SLLGNIRSDG
540
KISEQSDAKL
550
KEIVTNFLAG
FER
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005743 | mitochondrial inner membrane |
| Cellular Component | GO:0005886 | plasma membrane |
| Cellular Component | GO:0045259 | proton-transporting ATP synthase complex |
| Molecular Function | GO:0043532 | angiostatin binding |
| Molecular Function | GO:0005524 | ATP binding |
| Molecular Function | GO:0042288 | MHC class I protein binding |
| Molecular Function | GO:0046933 | proton-transporting ATP synthase activity, rotational mechanism |
| Biological Process | GO:0001937 | negative regulation of endothelial cell proliferation |
| Biological Process | GO:0043536 | positive regulation of blood vessel endothelial cell migration |
| Biological Process | GO:0042776 | proton motive force-driven mitochondrial ATP synthesis |
Reference
[1] Yao Y, Bade R, Li G, Zhang A, Zhao H et al.. Global-Scale Profiling of Differential Expressed Lysine-Lactylated Proteins in the Cerebral Endothelium of Cerebral Ischemia-Reperfusion Injury Rats.. Cell Mol Neurobiol 43(5):1989-2004. 2023 Jul. PMID: 36030297.