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Overview

Uniprot ID	F1LPP0
Protein Name	Amphiphysin
Gene Name	Amph
Organism	Rattus norvegicus

Kla Sites from experimental identification

Position	Flanking peptide
175	EEFQKAQKVFEEFNV
215	SLEAKFHKEIAVLCH

Function

May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton

Protein Sequence

10 MHGVSPRLTA 20 QTTQCWLQNK 30 VLQKLGKADE 40 TKDEQFEEYV 50 QNFKRQEAEG 60 TRLQRELRGY 70 LAAIKGMQEA 80 SMKLTESLHE 90 VYEPDWYGRE 100 DVKMVGEKCD 110 VLWEDFHQKL 120 VDGSLLTLDT 130 YLGQFPDIKN 140 RIAKRSRKLV 150 DYDSARHHLE 160 ALQSSKRKDE 170 SRISKAEEEF 180 QKAQKVFEEF 190 NVDLQEELPS 200 LWSRRVGFYV 210 NTFKNVSSLE 220 AKFHKEIAVL 230 CHKLYEVMTK 240 LGDQHADKAF 250 SIQGAPSDSG 260 PLRIAKTPSP 270 PEEASPLPSP 280 TASPNHTLAP 290 ASPAPVRPRS 300 PSQTRKGPPV 310 PPLPKVTPTK 320 ELQQENIINF 330 FEDNFVPEIN 340 VTTPSQNEVL 350 EVKKEETLLD 360 LDFDPFKPDV 370 TPAGSAAATH 380 SPMSQTLPWD 390 LWTTSTDLVQ 400 PASGGSFNDF 410 TQPQDTSLFT 420 MQTDQNMAET 430 EQALPTEPQA 440 EEPPTTAAAP 450 TAGLDLGLEM 460 EEPKEEAAIP 470 PGTDAGETVG 480 TEGSPGEEAE 490 AEKAALPAGE 500 GESPEGAKID 510 VESTELASSE 520 SPQAAELEAG 530 APQEKVIPSV 540 VIEPASNHEG 550 EEHQETTTGT 560 ETREATEDVA 570 PQGPAGEKQE 580 LATEPTPLDS 590 QAATPAPAGA 600 VDASLSAGDA 610 AQELPPGFLY 620 KVETLHDFEA 630 ANSDELTLQR 640 GDVVLVVPSD 650 SEADQDAGWL 660 VGVKESDWLQ 670 YRDLATYKGL 680 FPENFTRRRE

Gene Ontology

Classification	GO ID	Description
Cellular Component	GO:0005737	cytoplasm

Reference

[1] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.