Search Results
Overview
| Uniprot ID | F1LQC8 |
|---|---|
| Protein Name | Cyclin-dependent kinase 7 |
| Gene Name | Cdk7 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 329 | SNPAMATKRKRAEAL |
| 343 | LEQGILPKKLIF*** |
Function
No function data available.
Protein Sequence
10
MAVDVKSRAK
20
RYEKLDFLGE
30
GQFATVYKAR
40
DKNTNQIVAI
50
KKIKLGHRSE
60
AKDGINRTAL
70
REIKLLQELS
80
HPNIIGVSLM
90
HLDINRTLAL
100
SLILWRSTFQ
110
VIIKDNSLVL
120
TPSHIKAYML
130
MTLQGLEYLH
140
QHWILHRDLK
150
PNNLLLDENG
160
VLKLADFGLA
170
KSFGSPNRAY
180
THQVVTRWYR
190
APELLFGARM
200
YGVGVDMWAV
210
GCILAELLLR
220
VPFLPGDSDL
230
DQLTRIFETL
240
GTPTEEQWPD
250
MCSLPDYVTF
260
KSFPGIPLQH
270
IFIAAGDDLL
280
ELIQGLFLFN
290
PCTRITASQA
300
LRTKYFSNRP
310
GPTPGCQLPR
320
PNCPVEALKE
330
QSNPAMATKR
340
KRAEALEQGI
LPKKLIF
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0070516 | CAK-ERCC2 complex |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0001650 | fibrillar center |
| Cellular Component | GO:0048471 | perinuclear region of cytoplasm |
| Cellular Component | GO:0000439 | transcription factor TFIIH core complex |
| Cellular Component | GO:0070985 | transcription factor TFIIK complex |
| Molecular Function | GO:0005524 | ATP binding |
| Molecular Function | GO:0008094 | ATP-dependent activity, acting on DNA |
| Molecular Function | GO:0004693 | cyclin-dependent protein serine/threonine kinase activity |
| Molecular Function | GO:0140836 | RNA polymerase II CTD heptapeptide repeat S5 kinase activity |
| Biological Process | GO:0051301 | cell division |
| Biological Process | GO:0045944 | positive regulation of transcription by RNA polymerase II |
| Biological Process | GO:0050821 | protein stabilization |
| Biological Process | GO:2000045 | regulation of G1/S transition of mitotic cell cycle |
| Biological Process | GO:0006367 | transcription initiation at RNA polymerase II promoter |
Reference
[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.