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Overview

Uniprot ID	F1LUV9
Protein Name	Neural cell adhesion molecule 1
Gene Name	Ncam1
Organism	Rattus norvegicus

Kla Sites from experimental identification

Position	Flanking peptide
760	AFSKDESKEPIVEVR
810	EPQESEAKPAPTEVK

Function

This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc

Protein Sequence

10 KNSTKQRLGV 20 FELDFFFSFA 30 VSLQVDIVPS 40 QGEISVGESK 50 FFLCQVAGDA 60 KDKDISWFSP 70 NGEKLSPNQQ 80 RISVVWNDDD 90 SSTLTIYNAN 100 IDDAGIYKCV 110 VTAEDGTQSE 120 ATVNVKIFQK 130 LMFKNAPTPQ 140 EFKEGEDAVI 150 VCDVVSSLPP 160 TIIWKHKGRD 170 VILKKDVRFI 180 VLSNNYLQIR 190 GIKKTDEGTY 200 RCEGRILARG 210 EINFKDIQVI 220 VNVPPTVQAR 230 QSIVNATANL 240 GQSVTLVCDA 250 DGFPEPTMSW 260 TKDGEPIENE 270 EEDDEKHIFS 280 DDSSELTIRN 290 VDKNDEAEYV 300 CIAENKAGEQ 310 DASIHLKVFA 320 KPKITYVENQ 330 TAMELEEQVT 340 LTCEASGDPI 350 PSITWRTSTR 360 NISSEEKVQR 370 RPRVSGTLDG 380 HMVVRSHARV 390 SSLTLKSIQY 400 TDAGEYICTA 410 SNTIGQDSQS 420 MYLEVQYAPK 430 LQGPVAVYTW 440 EGNQVNITCE 450 VFAYPSATIS 460 WFRDGQLLPS 470 SNYSNIKIYN 480 TPSASYLEVT 490 PDSENDFGNY 500 NCTAVNRIGQ 510 ESLEFILVQA 520 DTPSSPSIDR 530 VEPYSSTAQV 540 QFDEPEATGG 550 VPILKYKAEW 560 KSLGEEAWHS 570 KWYDAKEANM 580 EGIVTIMGLK 590 PETRYAVRLA 600 ALNGKGLGEI 610 SAATEFKTQP 620 VREPSAPKLE 630 GQMGEDGNSI 640 KVNLIKQDDG 650 GSPIRHYLVK 660 YRAVTIVPTP 670 DIRRPGGRCH 680 WSQMPWLHTV 690 VNRVRANGSP 700 TAGLSTGAIV 710 GILIVIFVLL 720 LVVMDITCYF 730 LNKCGLLMCI 740 AVNLCGKAGP 750 GAKGKDMEEG 760 KAAFSKDESK 770 EPIVEVRTEE 780 ERTPNHDGGK 790 HTEPNETTPL 800 TEPEKGPVET 810 KSEPQESEAK 820 PAPTEVKTVP 830 NEATQTKENE SKA

Gene Ontology

Classification	GO ID	Description
Cellular Component	GO:0005886	plasma membrane
Molecular Function	GO:0008201	heparin binding
Biological Process	GO:0007155	cell adhesion
Biological Process	GO:0007399	nervous system development

Reference

[1] Yao Y, Bade R, Li G, Zhang A, Zhao H et al.. Global-Scale Profiling of Differential Expressed Lysine-Lactylated Proteins in the Cerebral Endothelium of Cerebral Ischemia-Reperfusion Injury Rats.. Cell Mol Neurobiol 43(5):1989-2004. 2023 Jul. PMID: 36030297.

[2] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.