Search Results
Overview
| Uniprot ID | F1M5T1 |
|---|---|
| Protein Name | Ferritin |
| Gene Name | Ftl1l2 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 144 | KEVKLIKKMGNHLTN |
| 59 | FRELAEEKREGAERL |
| 68 | EGAERLLKLQNERGG |
Function
Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation
Protein Sequence
10
MTSQIRQNYS
20
TEVEAAVNRL
30
VNLHLRASYT
40
YLSLGFFFDR
50
DDVALEGVGH
60
FFRELAEEKR
70
EGAERLLKLQ
80
NERGGRALFQ
90
DVQKPSQDEW
100
GKTLAAMEAA
110
LALEKNLNQA
120
LLDLHALGSA
130
RTDPHLCDFL
140
ESHFLDKEVK
150
LIKKMGNHLT
160
NLRRVAGPQP
170
VQTGVAQASL
180
GEYLFERLTL
KHD
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0044754 | autolysosome |
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0031410 | cytoplasmic vesicle |
| Molecular Function | GO:0008199 | ferric iron binding |
| Molecular Function | GO:0008198 | ferrous iron binding |
| Biological Process | GO:0006879 | intracellular iron ion homeostasis |
| Biological Process | GO:0006826 | iron ion transport |
Reference
[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.
[2] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.