Search Results
Overview
| Uniprot ID | F1M9D6 |
|---|---|
| Protein Name | Signal transducer and activator of transcription |
| Gene Name | Stat1 |
| Organism | Rattus norvegicus |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 193 | GVAKSDQKQEQLLLH |
Function
No function data available.
Protein Sequence
10
MSQWYELQQL
20
DSKFLEQVHQ
30
LYDDSFPMEI
40
RQYLAQWLEK
50
QDWEHAAYDV
60
SFATIRFHDL
70
LSQLDDQYSR
80
FSLENNFLLQ
90
HNIRKSKRNL
100
QDNFQEDPVQ
110
MSMIIHNCLK
120
EERKILENAQ
130
RFNQAQEGNI
140
QNTVMLDKQK
150
ELDSKVRNVK
160
DQVMCIEHEI
170
KTLEDLQDEY
180
DFKCKTSQNR
190
ESEANGVAKS
200
DQKQEQLLLH
210
KMFLMLDNKR
220
KEIIHKIREL
230
LNSIELTQNT
240
LINDELVEWK
250
RRQQSACIGG
260
PPNACLDQLQ
270
SWFTIVAESL
280
QQVRQQLKKL
290
EELEQKFTYE
300
QDPITKNKQV
310
LSDRTFVLFQ
320
QLIQSSFVVE
330
RQPCMPTHPQ
340
RPLVLKTGVQ
350
FTVKLRLLVK
360
LQELNYNLKV
370
KVSFDKDVNE
380
KNTVKGFRKF
390
NILGTHTKVM
400
NMEESTNGSL
410
AAEFRHLQLK
420
EQKNAGNRTN
430
EGPLIVTEEL
440
HSLSFETQLC
450
QPGLVIDLEV
460
FVHFQTTSLP
470
VVVISNVSQL
480
PSGWASILWY
490
NMLVTEPRNL
500
SFFLNPPCAW
510
WSQLSEVLSW
520
QFSSVTKRGL
530
NADQLSMLGE
540
KLLGPNAGPD
550
GLIPWTRFCK
560
ENINDKNFSF
570
WPWIDTILEL
580
IKKHLLCLWN
590
DGCIMGFISK
600
ERERALLKDQ
610
QPGTFLLRFS
620
ESSREGAITF
630
TWVERSQNGG
640
EPDFHAVEPY
650
TKKELSAVTF
660
PDIIRNYKVM
670
AAENIPENPL
680
KYLYPNIDKD
690
HAFGKYYSRP
700
KEAPEPMELD
710
DPKRTGYIKT
720
ELISVSEVHP
730
SRLQSTENLL
740
PMSPEEFDEM
750
SKIVGSEFDS
MMSAV
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Biological Process | GO:0002230 | positive regulation of defense response to virus by host |
| Cellular Component | GO:0030424 | axon |
| Cellular Component | GO:0000785 | chromatin |
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0030425 | dendrite |
| Cellular Component | GO:0070721 | ISGF3 complex |
| Cellular Component | GO:0016604 | nuclear body |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0005634 | nucleus |
| Cellular Component | GO:0048471 | perinuclear region of cytoplasm |
| Cellular Component | GO:0032991 | protein-containing complex |
| Cellular Component | GO:0090575 | RNA polymerase II transcription regulator complex |
| Molecular Function | GO:0031730 | CCR5 chemokine receptor binding |
| Molecular Function | GO:0003677 | DNA binding |
| Molecular Function | GO:0001228 | DNA-binding transcription activator activity, RNA polymerase II-specific |
| Molecular Function | GO:0003700 | DNA-binding transcription factor activity |
| Molecular Function | GO:0000981 | DNA-binding transcription factor activity, RNA polymerase II-specific |
| Molecular Function | GO:0003690 | double-stranded DNA binding |
| Molecular Function | GO:0019899 | enzyme binding |
| Molecular Function | GO:0035035 | histone acetyltransferase binding |
| Molecular Function | GO:0042393 | histone binding |
| Molecular Function | GO:0042802 | identical protein binding |
| Molecular Function | GO:1990841 | promoter-specific chromatin binding |
| Molecular Function | GO:0042803 | protein homodimerization activity |
| Molecular Function | GO:0051721 | protein phosphatase 2A binding |
| Molecular Function | GO:0000978 | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| Molecular Function | GO:0000979 | RNA polymerase II core promoter sequence-specific DNA binding |
| Molecular Function | GO:0000977 | RNA polymerase II transcription regulatory region sequence-specific DNA binding |
| Molecular Function | GO:0043565 | sequence-specific DNA binding |
| Molecular Function | GO:0001223 | transcription coactivator binding |
| Molecular Function | GO:0001222 | transcription corepressor binding |
| Molecular Function | GO:0005164 | tumor necrosis factor receptor binding |
| Molecular Function | GO:0044389 | ubiquitin-like protein ligase binding |
| Biological Process | GO:0008015 | blood circulation |
| Biological Process | GO:0008283 | cell population proliferation |
| Biological Process | GO:0007259 | cell surface receptor signaling pathway via JAK-STAT |
| Biological Process | GO:0097696 | cell surface receptor signaling pathway via STAT |
| Biological Process | GO:0032869 | cellular response to insulin stimulus |
| Biological Process | GO:0035458 | cellular response to interferon-beta |
| Biological Process | GO:0071222 | cellular response to lipopolysaccharide |
| Biological Process | GO:0071346 | cellular response to type II interferon |
| Biological Process | GO:0019221 | cytokine-mediated signaling pathway |
| Biological Process | GO:0006952 | defense response |
| Biological Process | GO:0051607 | defense response to virus |
| Biological Process | GO:0006351 | DNA-templated transcription |
| Biological Process | GO:0061484 | hematopoietic stem cell homeostasis |
| Biological Process | GO:0035722 | interleukin-12-mediated signaling pathway |
| Biological Process | GO:0070106 | interleukin-27-mediated signaling pathway |
| Biological Process | GO:0038111 | interleukin-7-mediated signaling pathway |
| Biological Process | GO:0038113 | interleukin-9-mediated signaling pathway |
| Biological Process | GO:0031663 | lipopolysaccharide-mediated signaling pathway |
| Biological Process | GO:0046725 | negative regulation by virus of viral protein levels in host cell |
| Biological Process | GO:0016525 | negative regulation of angiogenesis |
| Biological Process | GO:0043124 | negative regulation of canonical NF-kappaB signal transduction |
| Biological Process | GO:0001937 | negative regulation of endothelial cell proliferation |
| Biological Process | GO:0034240 | negative regulation of macrophage fusion |
| Biological Process | GO:0043065 | positive regulation of apoptotic process |
| Biological Process | GO:0008284 | positive regulation of cell population proliferation |
| Biological Process | GO:0045893 | positive regulation of DNA-templated transcription |
| Biological Process | GO:0045648 | positive regulation of erythrocyte differentiation |
| Biological Process | GO:0010628 | positive regulation of gene expression |
| Biological Process | GO:0032727 | positive regulation of interferon-alpha production |
| Biological Process | GO:0045429 | positive regulation of nitric oxide biosynthetic process |
| Biological Process | GO:0048661 | positive regulation of smooth muscle cell proliferation |
| Biological Process | GO:0045944 | positive regulation of transcription by RNA polymerase II |
| Biological Process | GO:0006468 | protein phosphorylation |
| Biological Process | GO:0042127 | regulation of cell population proliferation |
| Biological Process | GO:0006357 | regulation of transcription by RNA polymerase II |
| Biological Process | GO:0061326 | renal tubule development |
| Biological Process | GO:0009617 | response to bacterium |
| Biological Process | GO:0051591 | response to cAMP |
| Biological Process | GO:0034097 | response to cytokine |
| Biological Process | GO:0043330 | response to exogenous dsRNA |
| Biological Process | GO:0042542 | response to hydrogen peroxide |
| Biological Process | GO:0035456 | response to interferon-beta |
| Biological Process | GO:0070741 | response to interleukin-6 |
| Biological Process | GO:0032496 | response to lipopolysaccharide |
| Biological Process | GO:0009612 | response to mechanical stimulus |
| Biological Process | GO:0007584 | response to nutrient |
| Biological Process | GO:0043434 | response to peptide hormone |
| Biological Process | GO:0034340 | response to type I interferon |
| Biological Process | GO:0034341 | response to type II interferon |
| Biological Process | GO:0009410 | response to xenobiotic stimulus |
| Biological Process | GO:0045063 | T-helper 1 cell differentiation |
| Biological Process | GO:0033209 | tumor necrosis factor-mediated signaling pathway |
| Biological Process | GO:0060337 | type I interferon-mediated signaling pathway |
| Biological Process | GO:0060333 | type II interferon-mediated signaling pathway |
Reference
[1] Sheng L, Xu H, Wang Y, Ni J, Xiang T et al.. Systematic analysis of lysine lactylation in nucleus pulposus cells.. iScience 27(11):111157. 2024 Nov 15. PMID: 39524337.
[2] Chen Y, Sun W, Sun Z, Zhao H, Wu T et al.. Effect of electroacupuncture on hippocampal protein lactylation in a rat model of vascular dementia.. Front Neurol 16:1629474. 2025. PMID: 40963935.