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Overview

Uniprot IDF1REX9
Protein NameActin-related protein 2/3 complex subunit
Gene NameARPC1A
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
110 KWSPLENKFAVGSGA
174 RVFSAYIKEVDEKPA
290 VSKLDLPKQSIQRNL
36 NHEVHIYKKNGSQWV

Function

Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks

Protein Sequence

10 MSLHQFLLEP 20 ITCHAWNRDR 30 TQIALSPNNH 40 EVHIYKKNGS 50 QWVKAHELKE 60 HNGHITGIDW 70 APKSDRIVTC 80 GADRNAYVWS 90 QKDGVWKPTL 100 VILRINRAAT 110 FVKWSPLENK 120 FAVGSGARLI 130 SVCYFESEND 140 WWVSKHIKKP 150 IRSTVLSLDW 160 HPNNVLLAAG 170 SCDFKCRVFS 180 AYIKEVDEKP 190 ASTPWGSKMP 200 FGQLMSEFGG 210 SGTGGWVHGV 220 SFSASGSRLA 230 WVSHDSTVSV 240 ADASKSVQVS 250 TLKTEFLPLL 260 SVSFVSENSV 270 VAAGHDCCPM 280 LFNYDDRGCL 290 TFVSKLDLPK 300 QSIQRNLSAM 310 ERFRNMDKRA 320 TTEDRNTALE 330 TLHQNSITQV 340 SIYEVDKQDC 350 RKFCTTGIDG 360 AMTIWDFKVS 370 STFQNKSCLC

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005885 Arp2/3 protein complex
Cellular Component GO:0098978 glutamatergic synapse
Cellular Component GO:0036195 muscle cell projection membrane
Cellular Component GO:0005634 nucleus
Molecular Function GO:0051015 actin filament binding
Biological Process GO:0034314 Arp2/3 complex-mediated actin nucleation

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.