Search Results

Overview

Uniprot ID	F1RF24
Protein Name	Zinc finger FYVE domain-containing protein 16
Gene Name	ZFYVE16
Organism	Sus scrofa

Kla Sites from experimental identification

Position	Flanking peptide
1261	EMGKSCIKIPRKKYS

Function

May be involved in regulating membrane trafficking in the endosomal pathway. Overexpression induces endosome aggregation. Required to target TOM1 to endosomes

Protein Sequence

10 MESYFKAAVS 20 DLDKLLDDFE 30 RNPDEQDYLQ 40 DAQNAYDSNH 50 CSVSSELTSS 60 QLTSLLPKDQ 70 QCINCCASSE 80 TGYETNQISL 90 NEKTLEGLTS 100 VQNEKNVTGL 110 DLLSSVDGGT 120 SDEIQPLYMG 130 RCSKPVCDLI 140 SDMGDLVHVT 150 NSEEDIKKLL 160 PDDFKSSSDS 170 LIGLDLSSMS 180 ETFCASSTDH 190 GNTVREEQND 200 VSSELQNKGI 210 SGTKEFNIKV 220 DTTLSDLCNY 230 SGKEILKDKT 240 ISNQMEPVVD 250 FNMPVALTQQ 260 SSKVFDAKDH 270 LQHKNQPCEL 280 VKADGCLVKE 290 EVDVAIVAAT 300 DCLKEGGSAN 310 ALSCSPPKNG 320 GLCLNDSNLR 330 DENFKLPDFS 340 FQEDRSAIFI 350 KQSATEESSN 360 LDLQDNKDVI 370 QDTTSTLCVS 380 SENMYSSLSC 390 LPVPGSLCGS 400 LIGSKVQDDC 410 LPQNEYKDNI 420 KDAVTVHEEV 430 EENVAPGGEP 440 LKETDLLKQE 450 KCKNILHQPL 460 IEKMEDRKVD 470 SDQMVIRAES 480 LNHPGNSSST 490 AAESQVELSG 500 ANAPESPDHC 510 EGLTFSSSDI 520 DGQDLDYFNI 530 DEGMKGGAPI 540 SDAELDAFLT 550 EQYLQTSNIK 560 SFEENVNDSK 570 SQMNQIDIKG 580 LDDDGNVNDI 590 YFNAEAGATV 600 ESLGVSMICE 610 TVDKQNTTDN 620 GSLSLGEKST 630 VPVEQGLSST 640 KSEITNDLPV 650 SDINSQSVHV 660 GGARPKQLFS 670 VPSRTRSSKE 680 IYKPDVPNML 690 ESEPRIANTF 700 VAATCTTENA 710 TDPQVSFNSN 720 YIDIESNFEG 730 GSNFVTANEE 740 SLSANTCKEG 750 LLLGQKQPTW 760 VPDSEAPNCM 770 NCQVKFTFTK 780 RRHHCRACGK 790 VFCGVCCNRK 800 CKLQYLEKEA 810 RVCVVCYETI 820 SKAQAFERMM 830 SPTGSNLKSN 840 HSDECTNIQP 850 LQETHTSSIP 860 SPAALPISAL 870 KQPSVEGLCS 880 REQKRVWFAD 890 GILPNGEVAD 900 TTKLSSGSKR 910 CSEDISPVLP 920 DMPLMVNTVD 930 HPTTVEKSDN 940 EIGDIIRNEI 950 IRSPVSQIPT 960 VEKLRTNTAA 970 ESLPASGSSA 980 LDDDVFAEIE 990 EPSSASGVLV 1000 NSNVPVASPS 1010 DYRLLCGIDK 1020 SVCNKISLLP 1030 DDDDSLPPLL 1040 LTSGEKGSVP 1050 VVEEHPSHEQ 1060 VISLLEGEGF 1070 CPVTFVLNAN 1080 LLVNVKLAFY 1090 SSDKYWYFST 1100 NGLHGLGQAE 1110 IIILLLCLPN 1120 EDTIPKDIFR 1130 LFITIYKDAL 1140 KGKYIENLDN 1150 ITFTETFLSS 1160 KDHGGFLFIT 1170 PTFQKLDDLL 1180 LPSNPFLCGI 1190 LIQKLEIPWA 1200 KVFPMRLMLR 1210 LGTEYKAYPA 1220 PLTSVRGRKS 1230 LFGEIGHTIM 1240 NLLVDLRNYQ 1250 YTLHNIDQLF 1260 IHMEMGKSCI 1270 KIPRKKYSDV 1280 MKVINSSNEH 1290 VISIGASFST 1300 EADSHLVCVQ 1310 NDGVYQTQAN 1320 CATGHPRKVT 1330 GASFVVFNGA 1340 LKASSGFLAK 1350 SSIVEDGLMV 1360 QITPETMDGL 1370 RLALREQKDF 1380 KITCGKADAV 1390 DMREYVDICW 1400 VDSEEKGNKG 1410 VISSVDGISL 1420 QGFPSEKIKL 1430 EADFETDEQT 1440 VKCTEVFYFL 1450 KDQDLSLSAT 1460 RYQFAKEIAM 1470 ACSAALCPHL 1480 KTLKCNGMNK 1490 IGLRVSIDTD 1500 MVEFQAGSEG 1510 QLLPQHYLND 1520 LDSALIPVIH 1530 GGTSNTTSLP 1540 LEIELVFFII ENLF

Gene Ontology

Classification	GO ID	Description
Cellular Component	GO:0005829	cytosol
Cellular Component	GO:0031901	early endosome membrane
Molecular Function	GO:0005545	1-phosphatidylinositol binding
Molecular Function	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding
Molecular Function	GO:0008270	zinc ion binding
Biological Process	GO:0016197	endosomal transport
Biological Process	GO:0006622	protein targeting to lysosome

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.