Search Results
Overview
| Uniprot ID | F1RJT3 |
|---|---|
| Protein Name | Dihydropyrimidinase-related protein 2 |
| Gene Name | DPYSL2 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 363 | YITKVMSKSAAEVIA |
| 375 | VIAQARKKGTVVYGE |
| 577 | SGRYIPRKPFPDFVY |
| 625 | VTPASSAKTSPAKQQ |
| 630 | SAKTSPAKQQAPPVR |
Function
Plays a role in neuronal development and polarity, as well as in axon growth and guidance, neuronal growth cone collapse and cell migration. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. May play a role in endocytosis
Protein Sequence
10
MAERKQSGKA
20
AEDEEVPAFF
30
KNLGSGSPKP
40
RQKFCGMFCP
50
VEGSSENKTI
60
DFDSLSVGRG
70
SGQVVAQQRD
80
VAHLGPDPQP
90
PYSRQGRRAG
100
GEPSVESGRK
110
VEIRRASGKE
120
ALQNINDQSD
130
RLLIKGGKIV
140
NDDQSFYADI
150
YMEDGLIKQI
160
GENLIVPGGV
170
KTIEAHSRMV
180
IPGGIDVHTR
190
FQMPDQGMTS
200
ADDFFQGTKA
210
ALAGGTTMII
220
DHVVPEPGTS
230
LLSAFDQWRE
240
WADSKSCCDY
250
SLHVDITEWH
260
KGIQEEMEAL
270
VKDHGVNSFL
280
VYMAFKDRFQ
290
LTDSQIYEVL
300
SVIRDIGAIA
310
QVHAENGDII
320
AEEQQRILDL
330
GITGPEGHVL
340
SRPEEVEAEA
350
VNRSITIANQ
360
TNCPLYITKV
370
MSKSAAEVIA
380
QARKKGTVVY
390
GEPITASLGT
400
DGSHYWSKNW
410
AKAAAFVTSP
420
PLSPDPTTPD
430
FLNSLLSCGD
440
LQVTGSAHCT
450
FNTAQKAVGK
460
DNFTLIPEGT
470
NGTEERMSII
480
WDKAVVTGKM
490
DENQFVAVTS
500
TNAAKVFNLY
510
PRKGRIAVGS
520
DADLVIWDPD
530
SVKTISAKTH
540
NSSLEYNIFE
550
GMECRGSPLV
560
VISQGKIVLE
570
DGTLHVTEGS
580
GRYIPRKPFP
590
DFVYKRIKAR
600
SRLAELRGVP
610
RGLYDGPVCE
620
VSVTPKTVTP
630
ASSAKTSPAK
640
QQAPPVRNLH
650
QSGFSLSGAQ
660
IDDNIPRRTT
670
QRIVAPPGGR
ANITSLG
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0030424 | axon |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0030425 | dendrite |
| Cellular Component | GO:0045171 | intercellular bridge |
| Cellular Component | GO:0072686 | mitotic spindle |
| Cellular Component | GO:0043025 | neuronal cell body |
| Cellular Component | GO:0014069 | postsynaptic density |
| Cellular Component | GO:0098685 | Schaffer collateral - CA1 synapse |
| Molecular Function | GO:0016810 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds |
| Molecular Function | GO:0019901 | protein kinase binding |
| Biological Process | GO:0030154 | cell differentiation |
| Biological Process | GO:0007010 | cytoskeleton organization |
| Biological Process | GO:0007399 | nervous system development |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.