Search Results
Overview
| Uniprot ID | F1RLQ5 |
|---|---|
| Protein Name | - |
| Gene Name | POGLUT2 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 181 | KIATEIPKRFGQRQS |
Function
Protein glucosyltransferase that catalyzes the transfer of glucose from UDP-glucose to a serine residue within the consensus sequence peptide C-X-N-T-X-G-S-F-X-C. Can also catalyze the transfer of xylose from UDP-xylose but less efficiently. Specifically targets extracellular EGF repeats of proteins such as NOTCH1, NOTCH3, FBN1, FBN2 and LTBP1. May regulate the transport of NOTCH1 and NOTCH3 to the plasma membrane and thereby the Notch signaling pathway
Protein Sequence
10
MFSILLLYCF
20
FLGTVPTLAE
30
TGGERRVSPE
40
KSEIWGPGLK
50
AAVVLPARYF
60
YIQAVDTSGN
70
KFTTSPGDKV
80
FQIKISAPDE
90
QFTRVGVQVL
100
DRKDGSFIVR
110
YRMYASYKNL
120
KVEVKFQGQH
130
VAKSPYILKG
140
PVYHENCDCP
150
LEDAAAWLRE
160
MSCPETIPQI
170
QRDLAQFPSV
180
DPEKIATEIP
190
KRFGQRQSLC
200
HYTLKDNKVY
210
IKTHGEHVGF
220
RIFMDAILLS
230
LTRKVKMPDV
240
EFFVNLGDWP
250
LEKKKSGSHI
260
HPIFSWCGST
270
DSKDIVMPTY
280
DLTDSVLETM
290
GRVSLDMLSV
300
QANTGPPWES
310
KNSTAVWRGR
320
DSRKERLELV
330
KLSRKHPELI
340
DAAFTNFFFF
350
KHDESLYGPI
360
VKHISFFDFF
370
KHKYQINVDG
380
TVAAYRLPYL
390
LVGDSVVLKQ
400
DSIYYEHFYN
410
ELQPWKHYIP
420
VRSNLSDLLE
430
KLKWAKDHDE
440
EAKKIAKTGQ
450
EFARNNLMGD
460
DIFCYYFKLF
470
QEYASLQVSE
480
PQIREGMERV
490
QPQTEDDLFP
500
CACHRKKTKD
EL
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0012505 | endomembrane system |
| Cellular Component | GO:0005788 | endoplasmic reticulum lumen |
| Cellular Component | GO:0005654 | nucleoplasm |
| Molecular Function | GO:0046527 | glucosyltransferase activity |
| Molecular Function | GO:0035251 | UDP-glucosyltransferase activity |
| Molecular Function | GO:0035252 | UDP-xylosyltransferase activity |
| Biological Process | GO:0180059 | protein O-linked glycosylation via glucose |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.