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Overview

Uniprot IDF1RLZ7
Protein Name-
Gene NameDPYSL3
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
115 EIRSATGKEVLQNLG
124 VLQNLGPKDKSDRLL
133 KSDRLLIKGGRIVND
270 QEVQGLIKDKGVNSF
371 YVTKVMSKSAADLIS
600 KRIKARRKMADLHAV

Function

Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration

Protein Sequence

10 MASGRRGWDS 20 SHEDDLPVYL 30 ARPGTTDQVP 40 RQKYGGMFCN 50 VEGAFESKTL 60 DFDASVGQRG 70 AKTPRSSQGS 80 GRGSASRPGA 90 EGDTPRRGQG 100 REESREPAPA 110 SPAPAGVEIR 120 SATGKEVLQN 130 LGPKDKSDRL 140 LIKGGRIVND 150 DQSFYADIYM 160 EDGLIKQIGD 170 NLIVPGGVKT 180 IEANGKMVLP 190 GGIDVHTHFQ 200 MPYKGMTTVD 210 DFFQGTKAAL 220 AGGTTMIIDH 230 VVPEPESSLT 240 EAYEKWREWA 250 DGKSCCDYSL 260 HVDITHWSDS 270 VKQEVQGLIK 280 DKGVNSFMVY 290 MAYKDLYQVS 300 NTELYEIFTC 310 LGELGAIAQV 320 HAENGDIIAQ 330 EQTRMLEMGI 340 TGPEGHVLSR 350 PEELEAEAVF 360 RAITIASQTN 370 CPLYVTKVMS 380 KSAADLISQA 390 RKKGNVVFGE 400 PITASLGTDG 410 THYWSKNWAK 420 AAAFVTSPPL 430 SPDPTTPDYI 440 NSLLASGDLQ 450 LSGSAHCTFS 460 TAQKAIGKDN 470 FTAIPEGTNG 480 VEERMCVIWD 490 KAVATGKMDE 500 NQFVAVTSTN 510 AAKIFNLYPR 520 KGRISVGSDS 530 DLVIWDPDAV 540 KIVSAKNHQS 550 AAEYNIFEGM 560 ELRGAPLVVI 570 CQGKIMLEDG 580 NLHVTQGAGR 590 FIPCSPFSDY 600 VYKRIKARRK 610 MADLHAVPRG 620 MYDGPVFDLT 630 TTPKGGTPAG 640 STRGSPTRPN 650 PPVRNLHQSG 660 FSLSGTQVDE 670 GVRSASKRIV 680 APPGGRSNIT SLS

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005737 cytoplasm
Cellular Component GO:0030426 growth cone
Molecular Function GO:0031005 filamin binding
Molecular Function GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
Molecular Function GO:0051219 phosphoprotein binding

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.