Search Results

Overview

Uniprot ID	F1RQQ7
Protein Name	Alpha-1,4 glucan phosphorylase
Gene Name	PYGB
Organism	Sus scrofa

Kla Sites from experimental identification

Position	Flanking peptide
493	VKQENKVKFSAFLEK
761	RNIACSGKFSSDRTI

Function

Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis

Protein Sequence

10 MAKPLTDGER 20 RKQISVRGLA 30 GLGDVAEVRK 40 SFNRHLHFTL 50 VKDRNVATRR 60 DYYLALAHTV 70 RDHLVGRWIR 80 TQQHYYERDP 90 KVRRRRGGGC 100 PGVGRFPPCT 110 VCTLGSALSP 120 GLSPRDPPVA 130 AALQVEEADD 140 WLRYGNPWEK 150 ARPEYTLPVH 160 FYGRVEHSAE 170 GVRWLDTQVV 180 LAMPYDTPVP 190 GYKNDTVNTM 200 RLWSAKAPND 210 FKLHDFNVGG 220 YIEAVLDRNL 230 AENISRVLYP 240 NDNFFEGKEL 250 RLKQEYFVVA 260 ATLQDVIRRF 270 KSAKFGCRDP 280 VRTSFDTFPD 290 KVAIQLNDTH 300 PALAIPELMR 310 ILVDVEKVDW 320 DKAWDITKKT 330 CAYTNHTVLP 340 EALERWPVSM 350 FEKLLPRHLE 360 IIYAINQRHL 370 DHVAALFPGD 380 VDRLRRMSVI 390 EEGDCKRINM 400 AHLCVIGSHA 410 VNGVARIHSE 420 IVKHSVFKDF 430 YELEPEKFQN 440 KTNGITPRRW 450 LLLCNPGLAD 460 TIMERIGEGF 470 LTDLSQLRKL 480 LPLVNDEALI 490 RDVAQVKQEN 500 KVKFSAFLEK 510 EYGVKVNPAS 520 MFDVHVKRIH 530 EYKRQLLNCL 540 HVVTLYNRIK 550 KDPGQAFVPR 560 TVMIGGKAAP 570 GYHMAKMIIK 580 LVTSIGDIVN 590 HDPVVGGRLK 600 VIFLENYRVS 610 LAEKVIPAAD 620 LSQQISTAGT 630 EASGTGNMKF 640 MLNGALTIGT 650 MDGANVEMAE 660 EAGAENLFIF 670 GLRVEDVEAL 680 DRKGCVYNAR 690 EYYERLPELR 700 QAVDQISNGF 710 FSPRKPDCFK 720 DLVDMLLNHD 730 RFKVFADYEA 740 YVACQARVDQ 750 LYQDPKEWTK 760 KVIRNIACSG 770 KFSSDRTITE 780 YARDIWGVEP 790 SAQQAQAPSL PRD

Gene Ontology

Classification	GO ID	Description
Molecular Function	GO:0008184	glycogen phosphorylase activity
Molecular Function	GO:0030170	pyridoxal phosphate binding
Biological Process	GO:0005977	glycogen metabolic process

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.